research New Antifungal Agents and Formulations Against Dermatophytes
New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.
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research Phenotype and Metabolic Profile of South Asian Women with Polycystic Ovary Syndrome: Results from a Specialist Endocrine Clinic
South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.
research Preventing the Development of Complex Regional Pain Syndrome After Surgery
Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.
research 5α-Reductase Isozymes and Androgen Actions in the Prostate
5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
research Sex Hormone-Binding Globulin: An Important Biomarker for Predicting PCOS Risk - A Systematic Review and Meta-Analysis
Lower SHBG levels may increase the risk of PCOS.
research TNF Superfamily in Skin Appendage Development
TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
research Androgen Receptors And Their Biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research Review Article: Dermatological Complications of Immunosuppressive and Anti-TNF Therapy in Inflammatory Bowel Disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
research Autoimmunity and Autoimmune Co-Morbidities in Psoriasis
Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.
research Dermatologic Care for Lesbian, Gay, Bisexual, and Transgender Persons
LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.
research Environmental Stress But Not Subjective Distress in Children or Adolescents With Alopecia Areata
Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.
research Trichoscopy in Hair Shaft Disorders
Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.
research Prognosis and Management of Congenital Hair Shaft Disorders with Fragility—Part I
Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.
research Neurosteroids Are Endogenous Neuroprotectants in an Ex Vivo Glaucoma Model
A natural steroid in the body may protect against eye damage in glaucoma.
research Modeling of Chronic Radiation-Induced Cystitis in Mice
Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
research Intragenic Deletion in the Desmoglein 4 Gene Underlies the Skin Phenotype in the Iffa Credo Hairless Rat
A gene deletion causes the "hairless" trait in Iffa Credo rats.
research A Systematic Review of the Outcome of Hair Transplantation in Primary Scarring Alopecia
Hair transplantation may work for some types of scarring alopecia, but results vary and more research is needed.
research Skin Diseases Associated With Hepatitis C Virus: Facts and Controversies
Hepatitis C virus can cause skin diseases and dermatologists play a crucial role in identifying these conditions.
research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Riboflavin-Responsive Glutaryl CoA Dehydrogenase Deficiency
Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.
research Regulatory T Cells in Autoimmune Skin Diseases
Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Pharmacological Activation of Estrogen Receptors-α and -β Differentially Modulates Keratinocyte Differentiation with Functional Impact on Wound Healing
Activating ER-β, not ER-α, improves skin cell growth and wound healing.
research A Use-And-Transformation Model For Evaluating Public R&D: Illustrations From Polycystic Ovarian Syndrome (PCOS) Research
The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.
research Focal Hypertrichosis During Topical Tacrolimus Therapy for Childhood Vitiligo
An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
research Androgens Modulate Keratinocyte Differentiation Indirectly Through Enhancing Growth Factor Production From Dermal Fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
research Alopecia Areata But Not Androgenetic Alopecia Is Characterized By A Restricted And Oligoclonal T-Cell Receptor-Repertoire Among Infiltrating Lymphocytes
Alopecia areata involves specific T-cells, unlike androgenetic alopecia.
research Leucaena Leucocephala: A Nutritional Profile
Leucaena leucocephala is nutritious but needs careful processing to remove toxins.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.