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The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Targeted cancer therapies often cause serious skin problems that need careful management.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair loss needs more research for better treatments.

AXR3 and SHY2 genes control the growth and timing of root hair development in plants.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Humans lost body hair relatively recently in evolution.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Too much androgen can cause hair loss; finasteride may help.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Different types of stem cells and their environments are key to skin repair and maintenance.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Male pattern baldness involves hormones and cell signals affecting hair growth.