January 2017 in “Elsevier eBooks” This chapter discusses charnolopharmacotherapeutics for various medical conditions and suggests antioxidant-loaded nanoparticles may improve treatment by enhancing central nervous system delivery and inducing charnolophagy.
6 citations
,
May 2014 in “Biomarkers and Genomic Medicine” This review discusses Charnoly bodies as biomarkers of cell injury and potential therapeutic targets in neurodegenerative, cardiovascular, and cancer treatments but reports no new clinical results.
1 citations
,
January 2018 in “International Journal of Trichology” This report discusses the characteristics of circle hairs, a type of body hair growth disorder, and emphasizes the value of trichoscopy for diagnosis.
27 citations
,
December 1999 in “American Journal of Dermatopathology” This case report presents a patient with necrobiosis lipoidica exhibiting transepithelial elimination of cholesterol crystals through hair follicles, a finding previously associated with necrobiotic xanthogranuloma.
34 citations
,
June 1992 in “Journal of Cutaneous Pathology” In this case study, electron microscopy revealed that harlequin ichthyosis involves giant mitochondria in keratinocytes and abnormal lamellar granule development, which may contribute to pathogenesis through altered lipid metabolism.
January 2006 in “Dianzi xianwei xuebao” This study observed that ultrastructural changes like lamellar bodies and electron-dense granules in the stratum corneum may aid in the early diagnosis of Netherton syndrome.
36 citations
,
December 2004 in “British Journal of Dermatology” This case study reports a peculiar variant of an epidermal cyst in a patient, featuring unique characteristics like brownish, lumpy contents resembling bone marrow.
7 citations
,
May 1978 in “Acta Dermato Venereologica” This case report details a 36-year-old man with atypical necrobiosis lipoidica on his face, characterized by annular lesions and prominent giant cells without clear granuloma formation.
8 citations
,
August 1971 in “Canadian Journal of Zoology” This study reported the hematology and serum protein characteristics of chinchillas, including elevated transferrin to albumin concentration ratios during March and April, possibly linked to pregnancy or hair growth.
2 citations
,
June 2003 in “American Journal of Dermatopathology” This article reports a rare case of squamous cell carcinoma with miliary calcification in a cutaneous horn, suggesting possible involvement of calcium-binding proteins in this unique presentation.
6 citations
,
February 2020 in “Journal of Cutaneous Pathology” This case report describes the histopathological features of nevus psiloliparus in an 11-year-old girl, noting "shadow" follicular units with loosely arranged collagen and reduced elastic fibers.
October 2023 in “Indian dermatology online journal” This report describes a case study of a 23-year-old female exhibiting multiple trichodiscomas, a type of benign tumor of the hair follicular discs common in familial cases and potentially linked to Birt-Hogg-Dube syndrome, though genetic testing was not performed due to financial constraints.
2 citations
,
July 2001 in “Dermatologic Surgery” This study reports two cases of trichoblastic neoplasms with histologic features suggesting they may be distinct, locally aggressive trichoblastic carcinomas separate from basal cell carcinoma.
In this case study, a 15-year-old obese boy was diagnosed with acanthosis nigricans and hair casts in the axillae, with Wood's lamp and dermoscopic examination revealing specific features, yet fungal infection was ruled out through a negative KOH test.
34 citations
,
December 1984 in “Journal of Cutaneous Pathology” This study observed that the thinning and structural abnormalities in monilethrix-affected hair occur at the internodes due to possible periodic dysfunction of the hair matrix, particularly in the cortex.
1 citations
,
October 2022 in “Dermatology practical & conceptual” Isolated patchy heterochromia with pili annulati can occur without other health issues.
3 citations
,
March 2013 in “American Journal of Dermatopathology” This study found that ossification in trichilemmal cysts may be more common than previously thought, often associated with cyst wall rupture, and reports a novel case of ossifying TC with extramedullary hematopoiesis.
29 citations
,
February 1989 in “Journal of Cutaneous Pathology” This case report identifies a new type of hair matrix tumor called "rippled pattern trichomatricoma," distinguished by its unique cell arrangement and differentiation features.
August 2025 in “International Journal of Contemporary Pediatrics” This case report presents a rare subtype of hypomyelinating leukodystrophy linked to a PYCR2 gene mutation, emphasizing exome sequencing's value in diagnosing undiagnosed childhood HLDs with atypical symptoms.
November 2025 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” This study examined 16 sporadic trichoblastic tumors and found that although one showed malignant transformation, clinical follow-up revealed no residual or metastatic disease. RNA sequencing indicated a high tumor mutational burden and absence of a UV-related signature, helping to distinguish these tumors from similar growths.
6 citations
,
March 2016 in “PLoS ONE” This study characterized hair from a patient with a ribosomopathy and identified distinct differences, including reduced hair thickness and lipid content, compared to family members.
June 2023 in “Dermatopathology” In this case report, researchers described a unique skin lesion in a 55-year-old woman, identifying it as folliculosebaceous cystic hamartoma with an unusual combination of spindle cell lipomatous and neural components, which had not been previously documented in such cases.
1 citations
,
January 1986 in “PubMed” This case report describes a young patient with a unique combination of dysmorphism, bullous eruption, skin and muscle atrophy, and hyperpigmentation that doesn't fit existing nosological categories.
11 citations
,
January 1977 in “Archives of dermatological research” Mouse tail skin has different keratinization near hair follicles and scales.
19 citations
,
November 1985 in “Archives of Dermatology” This case study documented a black male newborn developing large bullae that healed with hypopigmentation, suspecting proteolytic enzymes in keratinocytes caused the collagenolysis responsible for the condition.
July 2023 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, researchers analyzed skin tumors from patients with CYLD cutaneous syndrome and found that loss of CYLD function is linked to changes in cellular signaling pathways, particularly NF-κB signaling, and leads to increased secretion of specific extracellular matrix proteins.
14 citations
,
January 1998 in “Dermatology” This study found evidence that polythelia pilosa, previously excluded from classification, should be reintroduced as it marks true aberrant mammary structures in men and hirsute women.
January 1980 in “中国科学A辑(英文版)” This study found that the molecular structures of α-keratin and collagen in a 2,100-year-old female cadaver's hair and tendon were preserved, while fibrous molecule aggregations were altered.
November 2021 in “Clinical, cosmetic and investigational dermatology” This case report details an 80-year-old woman with circle hair potentially linked to acquired ichthyosis from multiple myeloma, where a prescribed topical treatment led to clinical improvement.
September 2016 in “Journal of Dermatological Science” Polarizing light microscopy can easily and reliably diagnose congenital keratinizing disorders like Netherton syndrome.