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The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Men with androgenetic alopecia may have a higher risk of metabolic syndrome.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Researchers found 15 new genetic links to skin traits in Japanese women.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Obese women with PCOS are more likely to have fatty liver disease.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Men with testicular cancer were less likely to experience baldness and severe acne.

Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.

Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

The document concludes that more research is needed to fully understand the causes of PCOS.

Children with HIV often have skin problems that can indicate the severity of their immune system damage.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.