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    Glossary Caspase-8

    enzyme initiating programmed cell death, crucial for tissue health

    Caspase-8 is an enzyme that plays a crucial role in the process of programmed cell death, also known as apoptosis. It acts as an initiator caspase, meaning it helps to trigger the cascade of events that lead to cell death, which is essential for maintaining healthy tissue by removing damaged or unnecessary cells.

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    1. Making the head: Caspases in life and death Frontiers in Cell and Developmental Biology · 2023 · 7 citations
    2. Fundamental research on the action mechanism of the 800 nm semiconductor laser on skin blackheads and coarse pores Experimental and Therapeutic Medicine · 2016 · 1 citations
    3. Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells Skin Pharmacology and Physiology · 2006 · 58 citations
    4. Beneficial Effects of Astragaloside IV for Hair Loss via Inhibition of Fas/Fas L-Mediated Apoptotic Signaling PloS one · 2014 · 29 citations
    5. Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis Molecular Medicine Reports · 2017 · 18 citations
    6. Complex Changes in the Apoptotic and Cell Differentiation Programs during Initiation of the Hair Follicle Response to Chemotherapy Journal of Investigative Dermatology · 2014 · 12 citations
    7. Topical Treatment of Hair Loss with Formononetin by Modulating Apoptosis Planta Medica · 2016 · 10 citations
    8. Endocrinology & Metabolism News, August 2005 The Journal of Clinical Endocrinology & Metabolism · 2005 · 6 citations
    9. Effect of Liquid Blood Concentrates on Cell Proliferation and Cell Cycle- and Apoptosis-Related Gene Expressions in Nonmelanoma Skin Cancer Cells: A Comparative In Vitro Study International Journal of Molecular Sciences · 2024
    10. 1349 Stimulation of hair follicle stem cell proliferation through an IL-1α dependent activation of γδT-cells 2018
    11. Inflammation in androgenetic alopecia and hair loss: linking neurosciences-endocrinology-dermatology Hair transplant forum international · 2012 · 1 citations
    12. Expression of caspase-14 and keratin-19 in the human epidermis and appendages during fetal skin development Archives of Dermatological Research · 2013 · 19 citations
    13. Artificial Infestation of Sarcoptes scabiei (Acari: Sarcoptidae) in Rabbits Exhibits Progressive Pathological Changes, Apoptosis, and Keratinization in the Skin International journal of molecular sciences · 2023 · 1 citations
    14. Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis Journal of Pineal Research · 2019 · 46 citations
    15. Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury Journal of radiation research · 2017 · 19 citations
    16. Stem cell apoptosis in HIV‐1 alopecia Journal of Cutaneous Pathology · 2006 · 15 citations
    17. Sexual dimorphism following in vitro ischemia in the response to neurosteroids and mechanisms of injury BMC Neuroscience · 2020 · 6 citations
    18. Ameliorative Potential of Lycopene Against Finasteride-Induced Seminiferous Tubules Damage in Adult Rats: A Histological, Immunohistochemical, and Biochemical Study Microscopy and Microanalysis · 2025
    19. Pengaruh Ekstrak Metanol Batang Etlingera alba (Blume) A. D. Poulsen Terhadap Penekanan Genicaspase-3 sebagai Penanda Apoptosis pada Lini Sel Kanker Payudara T47D Secara In Vitro Jurnal Mandala Pharmacon Indonesia · 2025
    20. Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization Oxidative Medicine and Cellular Longevity · 2022 · 20 citations
    21. Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways Molecules · 2026
    22. Inflammasome Proteins as Biomarkers of Injury and Disease Springer eBooks · 2014
    23. Integrin-linked kinase inhibition via QLT0267 stops the epithelial outgrowth. OPAL (Open@LaTrobe) (La Trobe University) · 2015
    24. Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle Stem Cell Research & Therapy · 2021 · 11 citations
    25. Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson’s Disease Pharmaceuticals · 2023 · 17 citations
    26. A comparison of the cytotoxic effects of fatty acids on in vitro breast and prostate cell lines 2016 · 1 citations
    27. The concealed side of caspases: beyond a killer of cells Cellular and Molecular Life Sciences · 2024 · 13 citations
    28. Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue Journal of Molecular Histology · 2015 · 6 citations
    29. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice Journal of Immunology · 2015 · 59 citations
    30. ROS Balance Autoregulating Core–Shell CeO2@ZIF-8/Au Nanoplatform for Wound Repair Nano-Micro Letters · 2024 · 57 citations