Search
for

    Glossary Caspase-1

    enzyme activating inflammatory cytokines and inducing cell death

    Caspase-1, also known as Interleukin-1 converting enzyme (ICE), is an enzyme that plays a crucial role in the inflammatory response by activating pro-inflammatory cytokines like interleukin-1β (IL-1β) and interleukin-18 (IL-18). It is also involved in a form of programmed cell death called pyroptosis, which helps the body fight infections by eliminating infected cells.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice Journal of Immunology · 2015 · 59 citations
    2. Caspase-1 Level Is Higher in the Scalp in Androgenetic Alopecia Dermatologic Surgery · 2012 · 27 citations
    3. Distribution of caspase‐14 in epidermis and hair follicles is evolutionarily conserved among mammals 2005 · 21 citations
    4. Total glucosides of paeony inhibit NLRP3/caspase-1/GSDMD-mediated inflammation and pyroptosis in C3H/HeJ mice with alopecia areata Biomolecules and Biomedicine · 2024 · 5 citations
    5. Extracellular Caspase-1 induces hair stem cell migration in wounded and inflamed skin conditions The Journal of Cell Biology · 2024 · 4 citations
    6. Expression of apoptosis-related genes in the mouse skin during the first postnatal catagen stage, focused on localization of Bnip3L and caspase-12 Connective tissue research · 2015 · 4 citations
    7. Expression of caspase-14 and keratin-19 in the human epidermis and appendages during fetal skin development Archives of Dermatological Research · 2013 · 19 citations
    8. 647 NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing caspase-3 activity in human melanoma Journal of Investigative Dermatology · 2016 · 1 citations
    9. 1117 PX-12 inhibits NLRP3 inflammasome activation to treat psoriasis Journal of Investigative Dermatology · 2023
    10. 1446 RNase L acts as a regeneration suppressor Journal of Investigative Dermatology · 2023
    11. Stem cell apoptosis in HIV‐1 alopecia Journal of Cutaneous Pathology · 2006 · 15 citations
    12. 12-O-Tetradecanoylphorbol-13-acetate Induces Apoptosis in Renal Epithelial Cells through a Growth Signal Conflict Which Is Prevented by Activated ras1 Archives of Biochemistry and Biophysics · 2001 · 4 citations
    13. Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways Molecules · 2026
    14. 1349 Stimulation of hair follicle stem cell proliferation through an IL-1α dependent activation of γδT-cells 2018
    15. Cell death by cornification Biochimica et biophysica acta. Molecular cell research · 2013 · 375 citations
    16. Matrix remodelling and MMP expression/activation are associated with hidradenitis suppurativa skin inflammation Experimental Dermatology · 2019 · 51 citations
    17. Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease Frontiers in immunology · 2020 · 41 citations
    18. Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles Scientific reports · 2017 · 22 citations
    19. The Effect of JAK Inhibitor on the Survival, Anagen Re-Entry, and Hair Follicle Immune Privilege Restoration in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2020 · 16 citations
    20. Biofabrication of silver nanoparticles using Ostericum koreanum plant extract for treatment of allergic rhinitis in nursing care Materials Research Express · 2020 · 5 citations
    21. Umbilical cord mesenchymal stem cell-derived apoptotic extracellular vesicles ameliorate cutaneous wound healing in type 2 diabetic mice via macrophage pyroptosis inhibition Stem cell research & therapy · 2023 · 4 citations
    22. Inflammation in androgenetic alopecia and hair loss: linking neurosciences-endocrinology-dermatology Hair transplant forum international · 2012 · 1 citations
    23. Artificial Infestation of Sarcoptes scabiei (Acari: Sarcoptidae) in Rabbits Exhibits Progressive Pathological Changes, Apoptosis, and Keratinization in the Skin International journal of molecular sciences · 2023 · 1 citations
    24. RNase L represses hair follicle regeneration through altered innate immune signaling 2025
    25. RNase L represses hair follicle regeneration through altered innate immune signaling Journal of Clinical Investigation · 2025
    26. Inflammasome Proteins as Biomarkers of Injury and Disease Springer eBooks · 2014
    27. Co-editors’ Messages Hair transplant forum international · 2013
    28. Particulate matter exposure induces maternal scalp hair loss after birth in C57/B6 mouse via alteration of inflammatory and apoptotic pathways Frontiers in Endocrinology · 2026
    29. Immunomodulatory Effects of Platelet-Rich Plasma (PRP) on Neuroinflammation: Insights from B92 Glial Cells Stimulated with Heat-Killed Escherichia coli 2025
    30. Beneficial Effects of Astragaloside IV for Hair Loss via Inhibition of Fas/Fas L-Mediated Apoptotic Signaling PloS one · 2014 · 29 citations