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Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Polymeric nanoparticles show promise for treating skin diseases.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Sulforaphane from broccoli can help protect skin from sun damage.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.