39 citations
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January 2012 in “Dermatology” In this study, the combination of pulse intravenous corticosteroids and methotrexate was associated with positive hair regrowth in severe alopecia areata patients, with half achieving total regrowth.
31 citations
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January 1981 in “Pharmacology & Therapeutics” In this study, 13-cis-5S*,8S*-epidioxy-5,8-dihydroretinoic acid was found to be significantly more cytotoxic to cancer cell lines than other retinoic acid analogs evaluated.
12 citations
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July 2020 in “Actas Dermo-Sifiliográficas” This study found that facial papules and rosacea in patients with frontal fibrosing alopecia were linked to a greater need for oral treatment, with most cases involving postmenopausal women.
11 citations
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August 2004 in “Veterinary Dermatology” In this study, five out of six horses with equine sarcoidosis went into clinical remission with corticosteroid treatment, with some remaining in remission for years after therapy cessation.
2 citations
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October 2020 in “International Journal of Dermatology” This study found that lichen planopilaris in men typically presents similarly to women, with a lower likelihood of nonscalp hair loss and a higher association with mucosal lichen planus and thyroid disease.
2 citations
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October 2020 in “Research Journal of Health Sciences” This study documented that discoid lupus erythematosus was the most common cause of alopecia among patients at a dermatology outpatient clinic in Nigeria from 2014 to 2019.
July 2026 in “Journal of Investigative Dermatology” This retrospective cohort study found that individuals with alopecia totalis or universalis have a higher prevalence of systemic autoimmune diseases, particularly endocrine diseases and inflammatory bowel disease, compared to those with patchy alopecia areata.
January 2025 in “International Journal of Trichology” This retrospective study observed that telogen effluvium, a type of diffuse hair loss, frequently occurs in females aged 18–30 following SARS-CoV-2 infection, often accompanied by nutritional deficiencies, suggesting an association between COVID-19 and micronutrient deficiency, with acute cases being most common but chronic cases possible.
July 2023 in “Australasian Journal of Dermatology” This study described the incidence and prevalence of alopecia areata in Australia's primary healthcare population, finding the highest incidence in individuals aged 19 to 34, with males more affected than females.
In this retrospective cohort study of individuals diagnosed with late-onset systemic lupus erythematosus after age 80, most were women, joint and skin issues were prevalent, average survival was 4.5 years, and men had notably lower survival rates with higher mortality.
April 2023 in “Journal of Investigative Dermatology” This study reports distinctive clinical, trichoscopic, and histopathological features of fibrosing alopecia in a pattern distribution among Chinese patients, suggesting possible racial differences compared to previous studies primarily involving Caucasians.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that while 51.3% of severe alopecia areata patients achieved significant hair regrowth with intravenous methylprednisolone, oral Janus kinase inhibitors may benefit those who do not respond to this treatment.
46 citations
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September 2010 in “Veterinary Dermatology” This retrospective study documented various skin diseases in alpacas, reporting bacterial infections as the most common, along with other conditions described for the first time.
36 citations
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December 2017 in “Journal of the American Academy of Dermatology” This study observed that 70.7% of patients with frontal fibrosing alopecia stabilized with treatment, and patients using 0.3% tacrolimus were more likely to stabilize in 3 months compared to other treatments.
33 citations
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April 2020 in “Dermatitis” This study found that 9% of tested patients had positive patch test reactions linked to hair care products, with most reactions clinically relevant and commonly involving allergens like p-phenylenediamine.
27 citations
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December 2015 in “Clinical and Experimental Dermatology” This study found that hair regrowth occurred in 72.2% of alopecia areata patients treated with diphencyprone, with disease extent at baseline and duration affecting outcomes.
18 citations
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June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
16 citations
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October 2014 in “Journal of the American Academy of Dermatology” This study found that oral retinoid therapy may provide clinical improvement in a small percentage of patients with treatment-resistant lichen planopilaris, although it is not commonly used as a first-line treatment.
16 citations
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August 1989 in “PubMed” This study concluded that high-dose oral therapy with L-cystine, gelatin, and vitamin A significantly improved hair growth indicators in patients with diffuse hair loss, with no systemic side effects observed.
15 citations
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October 2016 in “PubMed” This study found that vitamin D, ferritin, and zinc deficiencies are prevalent among patients with telogen effluvium in the greater Pittsburgh area, suggesting these should be included in initial evaluations.
11 citations
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October 2011 in “Dermato-endocrinology” This study revealed that manual thyroid examinations in alopecia patients may uncover thyroid abnormalities undetectable by blood tests alone, but further research is needed to assess their clinical importance.
9 citations
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May 2002 in “PubMed” This study demonstrated that mice lacking skin-specific RXRalpha expression developed hair follicle degeneration and alopecia, indicating the importance of RXRalpha/VDR heterodimers in maintaining hair follicle homeostasis.
4 citations
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March 2024 in “Journal of the American Academy of Dermatology” Spironolactone for skin issues rarely causes low blood pressure.
3 citations
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March 2024 in “Journal of the American Academy of Dermatology” Low-dose naltrexone helps improve symptoms and stabilize frontal fibrosing alopecia and lichen planopilaris.
3 citations
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August 2020 in “Journal of The American Academy of Dermatology” This study observed that patients with scalp dysesthesia frequently exhibited cervical spine degenerative changes, which localized predominantly in the lower cervical spine, and reported modest symptom improvement with neuropathic pain medications and physical therapy.
2 citations
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July 2016 in “Veterinary dermatology” This study reports that hyperaesthetic leucotrichia primarily affects Arabian and American paint horses, occurring mainly in summer, with histological differences from erythema multiforme despite some shared features.
1 citations
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July 2023 in “Cosmetics” This study found that a novel shampoo formulation effectively delivers caffeine to hair follicles, with 8–9% of absorbed caffeine reaching the follicles, suggesting it may support hair retention by enhancing antioxidant activity.
1 citations
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January 2016 in “Open Forum Infectious Diseases” This study found that fluconazole induced early hair follicle resting phase (telogen effluvium) in rats, without changing retinoic acid levels in rats or human patients, suggesting further investigation into fluconazole's hair loss mechanism is needed.
June 2026 in “Journal of Cosmetic Dermatology” In this study, digital treatment for androgenetic alopecia over six months led to significant improvements in quality of life among Brazilian men, particularly for those with consistent program adherence, although the absence of an in-person comparator limits causal conclusions.
In this study, PRP combined with systemic therapy for androgenetic alopecia showed higher, but not statistically significant, improvements in hair density and width compared to PRP alone, with no increase in side effects; further prospective studies are recommended.