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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Some medicinal plants can help heal wounds and may lead to new treatments.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Anorexia nervosa can cause skin problems, which may help with early diagnosis and usually improve with treatment.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.