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PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Doctors need to be better prepared to assess and treat obesity in patients.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

SHBG may be a useful early indicator and treatment target for PCOS.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Some medications can cause acne, and stopping these drugs is the main treatment.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Quercetin may help with PCOS symptoms, but more research is needed.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.