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Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

A natural steroid in the body may protect against eye damage in glaucoma.

Psychotropic medications can cause skin reactions, including severe conditions like SJS and TEN, and it's important for psychiatrists to recognize and manage these side effects.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Hair loss in women not always linked to increased oil production; other factors may be involved.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.

New method detects finasteride in plasma quickly and accurately without clean-up.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

New compounds may soon be tested to treat excessive hair growth in women.

Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.