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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Follistatin helps hair growth and cycling, while activin prevents it.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

KCNQ potassium channels help control the sensitivity of touch receptors in the skin.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Iron deficiency common in women, not always linked to hair loss; more research needed.

Finasteride use is not clearly linked to an increased risk of male breast cancer.

Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Minoxidil use during pregnancy may cause fetal harm.

CDP is crucial for lung and hair follicle cell development.

The document concludes that improving patient safety and quality is increasingly important in dermatology.

Adults with certain skin conditions may have higher levels of inflammation in their body.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.

Acne in reproductive-age women may be linked to conditions like PCOS and lifestyle factors, so doctors should check for these when treating acne.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Abortion access should be defended on public health grounds, and medical evaluations are crucial in psychiatric cases to avoid misdiagnosis.

The document reviewed various health-related books, focusing on abortion debates, medical conditions, and effective health communication.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.

A group has developed therapies that show promise for treating cancer and various other conditions.