research Unmasking Melasma: Confronting the Treatment Challenges
Melasma treatment is difficult, but combination therapies and personalized plans show promise.
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research Age-Specific Cut-Off Levels of Anti-Müllerian Hormone as Diagnostic Markers for Polycystic Ovary Syndrome
Different levels of anti-Müllerian hormone can help diagnose polycystic ovary syndrome in women of different ages.
research Epidemiological Trends in Alopecia Areata at the Global, Regional, and National Levels
Cases of alopecia areata and its impact on life quality rose globally, but when adjusted for age, the rates decreased, especially in poorer regions.
research New and Consolidated Therapeutic Options for Pubertal Induction in Hypogonadism: In-Depth Review of the Literature
There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
research Multi-Ancestry Tandem Repeat Association Study of Hair Color Using Exome-Wide Sequencing
Tandem repeats significantly influence hair color, especially darker shades, across different ancestries.
research Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions
One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research Alopecia Areata Susceptibility Variant in MHC Region Impacts Expressions of Genes Contributing to Hair Keratinization and Is Involved in Hair Loss
A gene variant increases the risk of a type of hair loss by affecting hair protein production.
research TNF-Alpha in Nonscarring Inflammatory Alopecia
TNF-a may not be as involved in certain types of hair loss as previously thought.
research Topical Botanical Extract for Management of Chemotherapy-Induced Alopecia
A botanical extract may help manage hair loss from chemotherapy by preventing cell death in hair follicles.
research Platelet-Rich Plasma for Androgenetic Alopecia Treatment: A Randomized Placebo-Controlled Pilot Study
PRP injections did not significantly improve hair growth.
research Foundations of Bayesian Networks
Bayesian networks are tools for modeling variables' probabilistic relationships, which can efficiently represent complex probabilities and help in making inferences.
research Evaluation of the Predictive Capacity of DNA Variants Associated with Straight Hair in Europeans
Certain DNA variants can predict straight hair in Europeans but are not highly specific.
research Alopecia Associated With Treatment With Selective Serotonin Reuptake Inhibitors (SSRIs)
SSRIs can cause hair loss, especially sertraline, with higher risk in women.
research Alopecia in Association with Lamotrigine Use
Lamotrigine may cause hair loss, affecting treatment compliance and health.
research Spontaneous Lesions of Endangered Geriatric Julia Creek Dunnarts (Sminthopsis Douglasi, Archer 1979) with Emphasis on Reproductive Pathology
Geriatric Julia Creek dunnarts often suffer from reproductive and skin diseases, impacting conservation efforts.
research A Human Prenatal Skin Cell Atlas Reveals Immune Cell Regulation of Skin Morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research A Splice Variant in KRT71 Is Associated with Curly Coat Phenotype of Selkirk Rex Cats
A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.
research Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation
Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
research Editor's Evaluation: Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
research The Pioneer Factor SOX9 Competes for Epigenetic Factors to Switch Stem Cell Fates
SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
research Chi-miR-30b-5p Inhibits Dermal Papilla Cells Proliferation by Targeting CaMKIIδ Gene in Cashmere Goat
A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
research Skipping of Exons by Premature Termination of Transcription and Alternative Splicing Within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant
A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Multi-Scale Spatial Mapping of Cell Populations Across Anatomical Sites in Healthy Human Skin and Basal Cell Carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research An Improved Face Image Restoration Method Based on Denoising Diffusion Probabilistic Models
The new method improves facial image restoration quality and face recognition accuracy.
research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)
Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
research Tfap2b Specifies an Embryonic Melanocyte Stem Cell That Retains Adult Multi-Fate Potential
The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.