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This study found that basal cell carcinoma exhibits patterns of hair follicle differentiation but is stuck in telogen arrest, which can be rescued by adding noggin and TGF-β2 in vitro.

In this report, two adult patients with Tatton-Brown-Rahman syndrome exhibited new cardiac features, such as atrial fibrillation and ventricular and atrial dilatation, highlighting the importance of cardiovascular follow-up in adults with this condition.

In this study, Trapa bispinosa Roxb. pericarp extract demonstrated inhibitory effects on 5α-reductase activity both in vitro using LNCaP cells and in vivo in a mouse model of benign prostatic hyperplasia, suggesting its potential role in managing the condition.

The researchers reported that the novel MBTPS2 variant p.Glu172Asp found in a male proband is likely pathogenic, consistent with osteogenesis imperfecta symptoms and molecular signatures, including disrupted fatty acid metabolism and collagen production.

This study found that the catalytically inactive serine protease CAP1/Prss8 can still induce skin disorders in mice and is subject to inhibition by nexin-1, independent of its catalytic activity.

This report presents two cases of Berardinelli–Seip syndrome, emphasizing the role of genetic analysis and comprehensive care in managing the variability and complications of this rare condition.

This study found that MEGA PROTAC improved the prediction of ternary structures with higher maximum DockQ scores compared to the BOTCP method in 16 out of 22 test cases.

In this case report, researchers identified a novel homozygous missense mutation in the MBTPS2 gene associated with the mild form of IFAP syndrome in a 7-year-old boy.

Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.

This study used machine learning models, such as Convolutional Neural Networks (CNN), to accurately differentiate False Daisy from similar plants like Smooth Joyweed.

This study describes three new cases of MCOPS6 with BMP4 variants, noting expanded phenotypic variability but no clinically apparent microphthalmia in these individuals, which is commonly reported in the disorder.

In this study, BPA rapidly increased dendritic spine and synapse densities in cultured rat hippocampal neurons, with involvement of estrogen receptors and ERK1/2 and p38 pathways, but disrupted dihydrotestosterone's effects on synaptic plasticity.

KLHL24-mutant stem cells help understand skin and heart disease.

This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.

This study found that keratinocyte stem cells in mouse skin are closely related to side population or BCRP1-positive cells based on their localization and marker expression.

This study developed and validated a method using hair samples to simultaneously detect bisphenols and parabens, enabling the quantification of these endocrine disruptors in a hospital population’s hair.

This article introduces a revised NPRT classification system that includes diverse patterns of hair loss in both men and women, suggesting it as a universal tool for classification and documentation.

This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.

This article discusses the discontinuation of the Bexxar regimen for non-Hodgkin's lymphoma, noting that despite its effectiveness, it was under-prescribed due to marketing and development challenges without reporting new clinical results.

This study established consensus criteria for classifying alopecia areata severity, aiding clinicians in accurate diagnosis and treatment planning.

This case report describes a 40-year-old man with four autoimmune diseases leading to MAS, and suggests an additional classification category for MAS including autoimmune hypothyroidism, alopecia universalis, celiac disease, and immune thrombocytopenic purpura.

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This study developed a new multifunctional medical dressing using Bletilla striata polysaccharide and ethanol extract that demonstrated hemostatic, antibacterial, and significant wound healing effects, as evidenced by quicker healing rates and improved skin conditions in treated wounds compared to controls.

This study observed that basal cell carcinoma on the scalp shares more similar characteristics with truncal lesions than facial lesions, despite the scalp's proximity to the face.

This perspective discusses Villani et al.'s findings on the role of the IGF regulatory protein Igfbp2 in basal cell carcinogenesis and highlights potential therapeutic and preventive targets, while raising questions about the cell of origin.

This study found that Raman spectroscopy has potential for detecting biophysical differences in basal cell carcinoma compared to normal skin structures, supporting its future use in Mohs surgery.

This study suggests that the KAP 7 gene may serve as a potential molecular marker for genetic selection to improve staple length and greasy fleece weight in Rambouillet sheep.

This study reports a case of bovine besnoitiosis in Germany characterized by specific skin lesions, with diagnosis confirmed through histopathology, serology, and PCR as Besnoitia besnoiti.

This systematic review identified and evaluated the most accurate ICD code classification methods for dermatologic conditions in US-based datasets, highlighting both high-performing algorithms and areas lacking validation, thereby informing future research and dataset use.

The researchers reported that the facial Psoriasis Log-based Area and Severity Index (fPLASI) more reliably and sensitively captured clinical improvement in facial psoriasis than the existing facial Psoriasis Area and Severity Index (fPASI).