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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

A woman with breast cancer developed a rare condition causing excessive fine hair growth on her face and body.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.

Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Tedisamil and glibenclamide affect cromakalim and minoxidil sulphate differently in rat aorta.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Applying calreticulin can speed up wound healing in diabetics.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

Finasteride reduces hair growth and is safe for women with excessive hair.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

Hypaphorine from a fungus changes the internal structure of Eucalyptus root hairs, stopping their growth.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

Caffeine applied to the scalp can protect hair follicles from UV damage.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Hair follicles are valuable for regenerative medicine and wound healing.