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Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

TRH stimulates human hair growth and extends the hair growth phase.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Advanced human skin models improve drug development and could replace animal testing.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Skin problems are very common in people with end-stage kidney disease.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.