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The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Different types of stem cells and their environments are key to skin repair and maintenance.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

The circadian clock in skin cells controls their growth and rest cycles.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Minoxidil may help reduce aging effects in brain cells.

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Scientists found a gene in mice that causes early hearing loss.

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.

Wnt ligands are crucial for hair growth and repair.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.

The document concludes that recent studies help tell apart desmoplastic trichoepitheliomas from other skin tumors, but more research is needed for clear differentiation.

Bacteria can help skin regenerate through a process called IL-1β signaling.

Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.