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New treatments for a type of skin cancer show promise but have side effects and may work better with other therapies.

Activating Notch signaling can kill basal cell carcinoma cells.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Photodynamic therapy was effective in treating multiple scalp basal cell carcinomas with minimal side effects and good cosmetic results.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

The study found that analyzing certain cell signaling pathways is not a reliable method to tell apart two types of skin tumors.

CK 15, follistatin, and Bmi-1 can help differentiate basal cell carcinoma from squamous cell carcinoma.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

BerEP4 and CD34 staining can help tell apart tricholemmoma from basal cell carcinoma.

The research suggests new treatments for skin cancer could target specific cell growth pathways.

Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.

A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.

Dr. Connelly agrees that linear basal cell carcinomas might be more aggressive but highlights the study's lack of clear criteria to identify them.

The review found that basal cell carcinomas on the scalp are not more aggressive than those in other locations.

The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.

The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

Looking at tissue characteristics isn't reliable for telling apart basal cell carcinoma from certain benign skin tumors.

The antibody created from BCC tissues reacts similarly to both BCC and hair follicles, suggesting BCC may come from hair follicle cells.

The treatment was ineffective in humans.

Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.

A young man was unexpectedly diagnosed with basal cell carcinoma after a scalp examination and confocal microscopy.

Scalp basal cell carcinoma may be more aggressive and harder to treat than other types, requiring special attention and further research.

A rare type of skin cancer on the scalp can be mistaken for hair loss, causing delayed diagnosis and severe damage.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

The hedgehog signalling pathway is key in skin development and basal cell carcinoma, offering insights for prevention and treatment.