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GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

A young woman with kidney failure had hair loss due to a common hormonal disorder, which improved with hormone therapy.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.

Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.

Skin changes in women with PCOS are mainly due to hormonal imbalances.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Zinc can be a helpful secondary treatment for certain skin conditions, but more research is needed to guide its use.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

Proper care and diet are crucial to prevent health issues in gerbils.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

Blocking certain immune signals can reduce skin damage from radiation therapy.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

FoxN1 overexpression in young mice harms immune cell and skin development.

Hesperidin from orange peels is a promising natural ingredient for skincare due to its multiple beneficial properties.