January 2021 in “Revista Dermatológica Centro Uraga” This review emphasizes the importance of endocrinologic evaluation in acne patients due to its association with endocrine disorders like hyperandrogenism; it reports no new clinical results.
September 2020 in “Research Square (Research Square)” This study reported the expression patterns and potential functions of long non-coding RNAs in the hair follicle cycle of yak, with insights into their sequence conservation between yak and cashmere goat.
November 2019 in “Harper's Textbook of Pediatric Dermatology” This review discusses potential causes of alopecia and hair overgrowth in pediatric patients, detailing diagnostic techniques and treatments, but presents no new research findings.
October 2019 in “Skin appendage disorders” This study revisits and reproduces Felix Pinkus' concept of the vitreous membrane in hair follicles, suggesting these structures may play a role in differentiation or nutrition due to their location in metabolically dynamic regions.
March 2019 in “Journal of Investigative Dermatology” This review discusses a quiz related to seborrheic dermatitis diagnosis and key findings from a previous study, but reports no new clinical results.
January 2019 in “SAGE Open Medical Case Reports” This paper reports a rare case where AL amyloidosis presented as isolated scalp alopecia, underscoring the importance of considering systemic amyloidosis in the differential diagnosis of alopecia.
November 2016 in “Therapeutic Delivery” New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.
September 2016 in “Journal of dermatological science” This study found that COL17 plays a key role in regulating epidermal keratinocyte differentiation and proliferation, influencing the expression of differentiation markers and cellular growth in specific conditions.
September 2016 in “Journal of dermatological science” This study found that adult dermal papilla cells guided high-passage adult keratinocytes to produce new hair fibers, suggesting potential for large-scale hair follicle bioengineering.
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
January 2012 in “Methods in pharmacology and toxicology” This review discusses the use of cultured hair follicles for studying hair growth regulation and reports the challenge of modeling the entire hair cycle in vitro.
January 2010 in “Elsevier eBooks” The document concludes that different types of hair loss have specific treatments, and early diagnosis is crucial for preventing permanent hair loss.
May 2009 in “The American Journal of Dermatopathology” This abstract contains only journal subscription and informational content and does not present any research findings.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
January 2003 in “Elsevier eBooks” Androgens and other hormones affect hair growth and skin conditions like acne.
January 2021 in “Journal of cosmetology & trichology” In this follow-up study, participants with severe androgenic/estrogenic alopecia showed increased hair growth 10 months after ending vacuum therapy and cosmetic emulsion treatment, highlighting the therapies' potential effectiveness.
January 2007 in “Dermatologic Surgery” This study found that implanting polyamide hair fibers may serve as a supplementary treatment for scalp scars, with most cases showing favorable outcomes and manageable complications.
5 citations
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March 2019 in “Journal of lipid research” This study reports new fluorogenic ceramidase substrates and highlights RBM14C24:1 as an efficient substrate for neutral ceramidase, while RBM15C18:1 is the best probe for measuring ACER1 and ACER2 activities, potentially aiding high-throughput screening for ceramidase inhibitors.
September 2017 in “Journal of Investigative Dermatology” This study found that in AGA, the risk allele at locus 2q35 alters WNT10A expression through EBF1, suggesting a potential androgen-dependent regulatory mechanism.
72 citations
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January 2003 in “American Journal of Pathology” This study found that the co-activator CBP enhances the agonistic action of hydroxyflutamide on androgen receptors, suggesting a mechanism for therapy resistance in prostate cancer.
April 2018 in “Journal of Investigative Dermatology” This study observed that β-catenin overexpression in human squamous cell carcinoma cells led to increased CREB expression, which significantly enhanced clonogenic activity, suggesting CREB as a β-catenin-regulated factor promoting cancer characteristics.
April 2018 in “Journal of Investigative Dermatology” This study found that Basonuclin 1 knockdown in human primary keratinocytes significantly reduces cell proliferation and affects migration, indicating its role in coordinating the re-epithelization phase of wound healing.
14 citations
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March 2016 in “Mechanisms of Development” This study found that BNC2 is critical for hair follicle regeneration and other developmental processes, as Bnc2−/− mice exhibit incomplete hair follicle development and developmental defects, and BNC1 cannot substitute for BNC2.
November 2022 in “Journal of Investigative Dermatology” This study provides evidence that ILC1-like cells can induce alopecia areata in previously healthy human hair follicles, challenging the view that it is solely an autoantigen-dependent autoimmune disease.
1 citations
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March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that AtCEPs in Arabidopsis thaliana play a role in controlling root hair growth by processing EXT proteins, with NAC1 acting to regulate their expression and influence elongation.
27 citations
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October 1998 in “Differentiation” Basonuclin helps identify and track hair follicle development and cycling in mice.
January 1998 in “Differentiation” Basonuclin is crucial for hair follicle development and cycling in mice.
104 citations
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July 1994 in “The Journal of Cell Biology” This study suggests that basonuclin in keratinocytes is likely a regulatory molecule linked to maintaining proliferative capacity and preventing terminal differentiation rather than a cell cycle marker.