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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Hair loss needs more research for better treatments.

Zinc is effective for treating various skin conditions, including warts and acne.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Estrogen therapy can reduce skin aging but has cancer risks.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

To diagnose hair loss, use a systematic approach including history, exams, and tests.

Mutant mice help researchers understand hair growth and related genetic factors.

Animal models have helped understand hair loss from alopecia areata and find new treatments.