research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study
DHT may increase the risk of heart disease and death in elderly men.
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research Alopecia Areata: A Comprehensive Review of Pathogenesis and Management
New treatments for Alopecia Areata show promise but need to be more effective and affordable.
research Adverse Cutaneous Reactions to Soft Tissue Fillers: A Review of the Histological Features
Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.
research Physiological Changes in the Skin During Pregnancy
Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.
research Minoxidil: A Review of Its Pharmacological Properties and Therapeutic Use
Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
research Ginseng for Health Care: A Systematic Review of Randomized Controlled Trials in Korean Literature
Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.
research Sex Hormone-Binding Globulin: An Important Biomarker for Predicting PCOS Risk - A Systematic Review and Meta-Analysis
Lower SHBG levels may increase the risk of PCOS.
research Extracellular Matrix Degradation Products and Low-Oxygen Conditions Enhance the Regenerative Potential of Perivascular Stem Cells
Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
research Hair Cycle-Specific Expression of Versican in Human Hair Follicles
Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
research The Action of Diazoxide and Minoxidil Sulphate on Rat Blood Vessels: A Comparison with Cromakalim
Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
research Current Evaluation of Amenorrhea
Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.
research Hormonal Therapy for Acne: Why Not as First Line Therapy? Facts and Controversies
Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer, and Depression
5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
research Insulin Sensitizer Agents Alone and in Co-Treatment with Recombinant FSH for Ovulation Induction in Women with PCOS
Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research The Emerging Role of Janus Kinase Inhibitors in the Treatment of Autoimmune and Inflammatory Diseases
Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
research Polycystic Ovary Syndrome and Its Impact on Health
PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
research COVID-19 and Endocrine and Metabolic Diseases: An Updated Statement from the European Society of Endocrinology
People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
research Assessment of the Obese Patient
Doctors need to be better prepared to assess and treat obesity in patients.
research Toll-Like Receptor Function in Acute Wounds
Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
research Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine
Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
research Drug-Associated Alopecia
Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.
research Hormone Replacement Therapy for Women with Premature Ovarian Insufficiency: A Comprehensive Review
The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.
research Polycystic Ovary Syndrome: A Review for Dermatologists
Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.
research Ovarian Hypertension: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.
research Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
research Use of High-Dose Cyproterone Acetate and Risk of Intracranial Meningioma in Women: Cohort Study
High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.
research Cyclosporin: Applications in Small Animal Dermatology
Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
research Clinical Management of Patients with ASXL1 Mutations and Bohring-Opitz Syndrome, Emphasizing the Need for Wilms Tumor Surveillance
Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.