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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Oestrogens are key for bone growth during puberty in both boys and girls.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Cathepsin L is essential for normal hair growth and development.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Wool follicles are complex, involving interactions between different cell types and structures.

Mannosylerythritol lipids are good for skin and hair care products.

Four-amino acid part makes enzyme sensitive to finasteride.