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Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

A new compound effectively inhibits human 5α-reductase 1.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Increased PPARGC1α relates to hair thinning in common baldness.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Premature graying of hair is common and stressful, but not well understood or treated.

Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.

Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Oestrogens are key for bone growth during puberty in both boys and girls.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Skin has specialized touch receptors that can tell different sensations apart.

Methotrexate reduced the need for steroids in asthma patients without worsening their condition.

New treatments for male hypogonadism are effective and should be personalized.