19 citations
,
August 1999 in “European journal of endocrinology” This study concluded that neither basal nor ACTH-stimulated 17-OHP concentrations effectively indicate carrier status for 21-hydroxylase deficiency among Slovenian hyperandrogenic women, recommending molecular analysis of the CYP21 gene for reliable screening.
18 citations
,
February 2016 in “The Journal of Clinical Endocrinology and Metabolism” This article reviews emerging opportunities and challenges in male reproductive medicine, including advancements and unmet needs in erectile dysfunction, androgen deficiency, and fertility, but reports no new clinical findings.
18 citations
,
May 1992 in “American Journal of Biological Anthropology” This study found no general elevation in androgen levels among men predisposed to balding, despite a correlation with the free-to-total testosterone ratio; no link was observed with acne.
17 citations
,
August 2019 in “Archives of Cardiovascular Diseases” In this study, the authors observed that testosterone therapy shortened the QTc interval and normalized T-wave morphology in men with acquired LQTS or TdP linked to hypogonadism, suggesting testosterone may be helpful in treatment.
17 citations
,
October 2003 in “Contact dermatitis” Glycerin in hand cream can cause allergic skin reactions.
16 citations
,
September 2018 in “Scientific reports” This study demonstrates that keratinocyte cell lines derived from cultured hair follicles can fully differentiate in organotypic skin models, offering a minimally invasive alternative to obtaining keratinocytes for research.
16 citations
,
February 2018 in “European Journal of Endocrinology” This review discusses the challenges in measuring testosterone for assessing androgen excess in women and emphasizes the importance of quality control in laboratory methods, but it reports no new clinical results.
16 citations
,
January 2003 in “Nuclear Receptor Signaling” Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
15 citations
,
September 1984 in “Veterinary Clinics of North America: Small Animal Practice” The document explains various skin conditions in cats and how to diagnose and treat them.
13 citations
,
January 2018 in “BioMed Research International” This review summarizes recent findings on scalp involvement in pemphigus vulgaris and pemphigus foliaceus, highlighting diagnostic methods and their underlying histopathological, immunopathological, and clinical features, but reports no new clinical results.
12 citations
,
March 2018 in “Medicine” This case report describes a 60-year-old woman with an ovarian Leydig cell tumor leading to elevated testosterone levels and hirsutism, highlighting the need to consider androgen-secreting tumors in similar postmenopausal cases.
12 citations
,
October 2004 in “Experimental Gerontology” This review summarizes how common polymorphisms in androgen and estrogen receptor genes may influence aging-related symptoms and diseases in men, but it reports no new clinical results.
9 citations
,
January 2018 in “Journal of the European Academy of Dermatology and Venereology” A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.
9 citations
,
September 2009 in “PubMed” This case report presents the first evidence of significant antigen presenting cells around hair follicles in a patient with alopecia due to active systemic lupus erythematosus.
9 citations
,
September 1996 in “PubMed” In this study, finasteride treatment for male pattern baldness improved hair loss and reduced prostate size, while increasing testosterone levels and altering steroid hormone ratios without affecting gonadotropin levels.
7 citations
,
November 2006 in “Journal of immunological methods” This study found that the novel dot-block method can effectively measure early- and advanced-glycation products in hair, suggesting its potential for monitoring diabetes progression and other chronic conditions.
6 citations
,
January 2016 in “Evidence-based complementary and alternative medicine” In this study, saw palmetto supplements showed varied effects on cell growth in vitro and did not significantly inhibit growth in the hamster flank organ model despite a notable trend.
5 citations
,
July 2006 in “Contact dermatitis” This case report indicates that contact dermatitis on the face can result from using a bleaching ointment containing ammonium bisulfite during hair-dyeing.
5 citations
,
March 2001 in “Clinics in Dermatology” This article explores evidence for a rational strategy in the endocrine and metabolic management of patients with excess body hair or scalp loss and reports no new clinical results.
5 citations
,
January 1998 in “Clinical and experimental dermatology” This article discusses the late presentation of myotonic dystrophy but reports no new clinical findings.
3 citations
,
February 2023 in “Frontiers in Immunology” In this study, researchers reported that a newly developed interferon-γ release assay for cell-mediated immunity to SARS-CoV-2 nucleocapsid peptides demonstrated high sensitivity and specificity, making it a robust tool for routine diagnostic tests and potentially useful in predicting clinical outcomes after pathogen re-exposure.
3 citations
,
October 1995 in “Southern Medical Journal” Finasteride may cause breast enlargement, low testosterone a risk factor.
2 citations
,
September 2020 This Mendelian randomization study reports that lifelong increased free testosterone in males was associated with improved bone mineral density and body composition but increased risks of prostate cancer, hypertension, and several other conditions.
2 citations
,
September 2017 in “Archives of Medical Science” The researchers reported that finasteride treatment in male rats may lead to changes in antioxidant enzyme activity in their offspring's epididymis, potentially affecting sperm maturation.
2 citations
,
January 2013 in “Elsevier eBooks” This chapter reviews the causes and underlying steroid pathways of hirsutism and virilization in women, detailing relevant conditions and laboratory assays without reporting new clinical results.
2 citations
,
November 2015 in “Journal of Investigative Dermatology” This study found that RANKL signaling enhances CD8+ T cell-mediated anti-viral immunity during herpes simplex virus infection by preventing apoptosis of Langerhans cells, suggesting potential therapeutic applications.
1 citations
,
September 2023 in “Clinical, cosmetic and investigational dermatology” This genome-wide association study identified several genetic markers, including specific SNPs and HLA genotypes, associated with alopecia areata susceptibility in the Taiwanese population, highlighting key pathways involved in immune response and offering insights into the genetic origins of this autoimmune condition.
1 citations
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December 2018 in “Journal of Cosmetic Dermatology” In this study, androgenetic alopecia patients with thin hair were found to have a higher likelihood of experiencing prostatic enlargement and related urinary symptoms compared to those with thicker hair.
1 citations
,
November 2018 in “International research journal of pharmacy” This study found that PRP therapy was effective and safe for treating androgenic alopecia, promoting 30% hair growth and showing antimicrobial activity against certain bacteria in affected patients.
1 citations
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May 2017 in “InTech eBooks” The document explains the causes, types, diagnosis, and treatments of hair loss, and its psychological impact, especially on women.