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Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.

The peach gene pCTG134 helps control the interaction between auxin and ethylene hormones during fruit ripening.

Advancements in cosmetic and reconstructive surgery improve techniques and patient satisfaction.

Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.

Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

HIV can cause various severe or unusual skin conditions that help indicate the presence and stage of the disease.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Hormonal therapies are safe and effective for treating adult women's acne.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

The consensus document recommends a comprehensive treatment plan for Hidradenitis Suppurativa, including various medications, surgery, lifestyle changes, and the need for more research and resources.

Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

The conclusion is that better understanding and more research are needed to effectively manage follicular and scarring disorders in skin of color, with an emphasis on patient education and cultural awareness.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Most hair loss can be diagnosed with patient history and physical exam, and a few common types make up most cases.

Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.

The long-pulsed alexandrite laser is effective for hair reduction, particularly for light-skinned individuals with dark hair, but caution is needed for darker skin.

Malva verticillata seed extract might help treat hair loss by activating hair growth signals in skin cells.

Platelet-rich plasma (PRP) is a safe and potentially effective way to treat hair loss, especially when combined with minoxidil.