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Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Shen-Min, a hair growth supplement, likely caused acute hepatitis in a woman, improving after she stopped taking it.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Lithium therapy may cause skin problems like hidradenitis suppurativa and other side effects, which can improve after stopping the medication.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.

FOXN1 gene variants cause low T cells and immune issues from birth.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.