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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Ginsenoside F2 may help prevent hair loss and promote hair growth better than finasteride.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

The study created a new method to test drugs that affect hormone processing in skin.

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.

The research found that androgens help control blood flow in the rat prostate through a specific binding site.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

S100A3 protein is crucial for hair shaft formation in mice.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

MC4R gene variants not linked to female hair loss.

c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.