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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Hidradenitis suppurativa improves with antiandrogen therapy.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Excess male hormones in postmenopausal women can cause health issues and increase the risk of heart disease and diabetes; treatment depends on the cause.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Ectopic adrenal rests can cause androgen excess after adrenalectomy and may need targeted surgery.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.

Androgen use may increase the risk of stroke, but more research is needed.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.

Hair loss in women with PCOS is linked to high androgen levels but the relationship is unclear.

Removing the ovarian tumor improved the woman's hormonal symptoms.