Androgenic Alopecia Updates

Androgenic alopecia (AGA) is the most common type of hair loss in males, with increasing cases in females. It is characterized by a gradual reduction and noticeable absence of hair at the front of the head, due to a genetic predisposition and an increased sensitivity of hair follicles to androgens. While not lethal, AGA can have significant psychological and social impacts. The FDA has only authorized two medications for AGA, finasteride and minoxidil, which require extended use for improved therapy response. However, this can lead to inadequate treatment compliance and negative consequences, such as "post finasteride syndrome" even after discontinuing the medicine. Other treatment methods include the administration of Dutasteride, surgical hair transplant, and laser therapy. Current therapies for AGA are constrained by various factors, resulting in significant adverse responses.