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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Too much androgen can cause hair loss; finasteride may help.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Low-Level Laser Therapy (LLLT) is a safe and effective treatment for common hair loss, but more research is needed to find the best power and wavelength for treatment.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Higher caspase-1 levels found in balding scalps; reducing it may help treat hair loss.

Scalp hair grows at 0.37 mm/day, forearm hair at 0.18 mm/day, and thigh hair at 0.30 mm/day, with no significant differences found in people with certain hair conditions.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.