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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

Androgens may block hair growth signals, targeting this could treat hair loss.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

Treatment during development affects hormone balance and sexual behavior in male rats.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

AR gene not major factor in female hair loss; different from male hair loss.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Hsc70 protein may influence hair growth by responding to androgens.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.