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Anti-acne medications may work by reducing the activity of a protein involved in acne development.

The PCOS-specific questionnaire needs more work to fully measure quality of life in clinical trials.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.

Nonclassic congenital adrenal hyperplasia is a common genetic disorder that can cause a range of symptoms and requires personalized treatment.

Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Metformin helps manage weight, blood pressure, and hormonal imbalances in PCOS patients.

Adrenal disorders can cause lasting brain and behavior issues in children.

High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Women with PCOS often have liver disease, so liver health checks are important for them.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

The conclusion is to diagnose PCOS with just hyperandrogenism and irregular periods, and treat with lifestyle changes and basic medications.

PCOS is common in young women, especially those aged 21-30, and often involves symptoms like irregular periods, weight gain, and acne.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Blood AMH levels are higher in women with PCOS than in those with other similar conditions.

About 7% of Omani women visiting a gynecology clinic had polycystic ovarian syndrome, similar to rates in other countries.

About 3% of high school girls aged 14-18 in Isfahan, Iran, have polycystic ovary syndrome.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Metformin is safe in early pregnancy for women with PCOS and may reduce certain risks.

Frontal fibrosing alopecia is a challenging hair loss condition with no known cause or definitive treatment.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.