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Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

DHT stops hair regrowth in mice, similar to human hair loss.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Testosterone is crucial for development, growth, and various body functions in mammals.

The mouse models are effective for testing new hair loss treatments.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Researchers created five new human scalp cell lines that could be useful for hair growth and loss research.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.

Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.

Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.