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This study found that topical trypsin application after hair removal in mice led to cell death at the follicular papilla, which delayed hair growth and pigmentation.

This study observed that antisense oligonucleotides targeting FGFR-1 increased cellular activity in hair follicle cultures from mice, suggesting potential clinical utility for treating baldness.

Trichohyalin in hair can trigger immune attacks in alopecia areata.

This study reported that targeted anticancer therapies are associated with an increased risk of alopecia compared to placebo, although the risk was lower compared to chemotherapy.

In this study, a novel compound named AH-001 demonstrated effective androgen receptor protein degradation, reducing hair loss progression in a mouse model of androgenetic alopecia, with minimal systemic exposure and side effects, suggesting potential for safer treatment.

In this study, researchers identified two new keratin-associated proteins, hKAP1.6 and hKAP1.7, in human hair follicles, contributing to understanding hair fiber differentiation.

This study suggests that morphometric analysis using horizontal sectioning of scalp biopsies is effective for diagnosing alopecia in Koreans, but follicular count differences from Caucasians should be considered.

This study found that 82.3% of girls with anorexia nervosa had pili torti, an acquired hair defect, suggesting a potential link to excess vitamin A intake.

In their study, Tim Spector and colleagues identified a new genetic association at chromosome 20p11.22 with male-pattern baldness, confirmed by the increased risk when combined with a known androgen receptor gene variant.

This study observed that aromatase inhibitors caused hair loss in menopausal women with breast cancer, mimicking male pattern baldness rather than female androgenetic alopecia.

In this exploratory study, researchers found slightly increased levels of inflammatory markers in scalp skin affected by androgenetic alopecia, suggesting differential gene expression involved in hair cycle and keratin production.

This study found that dermal papillae in alopecia areata, including clinically normal follicles, exhibited ultrastructural abnormalities that suggest an early pathological role in the disease's development.

This study found that inhibiting the enzyme PDE8A can promote adipocyte differentiation and enhance hair growth in an animal model of androgenetic alopecia, suggesting PDE8A as a potential therapeutic target for restoring dermal adipogenesis and hair cycling.

This article highlights differences in childhood alopecia areata compared to adult cases but reports no new clinical findings.

This study reports that chemotherapy-induced alopecia in mice may be linked to decreased laminin-511 and increased laminin-332 around hair follicles, suggesting a potential mechanism for abrupt hair loss.

This study found that areola formation in mice requires a combination of pregnancy hormones and mechanical strain, with individual stimuli causing only modest changes in epidermal proliferation and connective tissue remodeling.

This article reviews the general, pathophysiological, diagnostic, and therapeutic aspects of alopecia frontal fibrosante, highlighting its irreversible nature and the importance of early diagnosis, but it reports no new clinical results.

This study identified a domain on human chromosome 21q22.1 containing various high glycine-tyrosine and high sulfur keratin-associated protein genes, revealing their diverse expression in hair-forming cells.

This study found that autophagy activation in hair follicle stem cells shifted their metabolism to glycolysis, which promoted hair growth by initiating the hair follicle cycle.

This study observed that applying a GMP-grade botanical extract to the scalp increased Bcl-2 levels, potentially preventing premature hair follicle apoptosis in chemotherapy and radiotherapy-induced alopecia.

This study describes a method using lentivirus in mouse cells to analyze epithelial-mesenchymal signaling important for hair follicle development, offering a quicker alternative to genetic models.

This study found that exposing dermal papilla cells to sub-lethal doses of colchicine releases histone H4, which inhibits cell growth and decreases alkaline phosphatase activity, potentially explaining colchicine-induced hair loss.

This study observed that while some progenitor cells were present in the partially bald areas of androgenic alopecia in Indian men, the completely bald areas lacked these cells, suggesting potential timing for therapeutic intervention targeting hair follicle stem cell activity.

In this case report, azathioprine induced sudden hair loss and pancytopenia in a 42-year-old female patient, but discontinuing the drug and providing supportive care resulted in complete recovery and hair regrowth within 2.5 months.

In this study, researchers demonstrated that CD4 T cells from skin-draining lymph nodes in mice with alopecia areata can transfer the disease to recipient mice, revealing a critical role for CD4 T cells in disease development and suggesting potential therapeutic targets.

This review discusses how sex-limited chromosomes can affect non-reproductive traits in various sex determination systems and reports no new empirical results.

This case report describes a patient with mutations in both alleles of the vitamin D receptor who exhibited hair loss clinically indistinguishable from generalized atrichia with papules, suggesting a potential genetic pathway shared with the hairless gene.