46 citations
,
October 2009 in “Archives of Dermatology” This study found that loose anagen hair syndrome is a common form of alopecia in young girls, typically presenting with thin, sparse hair and usually confirmed by a hair-pull test.
37 citations
,
July 2005 in “Journal of The American Academy of Dermatology” This article reviews the clinicopathologic features of short anagen syndrome in a child and suggests diagnostic methods like clinical examination and scalp hair growth rate measurement, without reporting new clinical results.
35 citations
,
February 2019 in “Cell Communication and Signaling” This study found that BMP6 and Wnt10b competitively regulate the transition between hair follicle growth phases, offering new insights into hair follicle cycling and potential hair loss treatments.
25 citations
,
May 2013 in “Experimental Dermatology” This study found that topical EGF-liposomal solution may protect hair follicles from chemotherapy-induced damage by inducing a catagen-like stage in a mouse model.
24 citations
,
September 1997 in “PubMed” This study concludes that loose anagen hair can develop in adulthood and may be difficult to distinguish from telogen hair loss, with pathologic findings offering limited diagnostic insights.
19 citations
,
April 1995 in “Clinical Genetics” This report describes two siblings with a new familial association of loose anagen syndrome and ocular coloboma, despite unaffected parents and no family history.
18 citations
,
March 2015 in “Journal of Dermatological Case Reports” This study identified distinctive trichoscopic features that may aid in diagnosing loose anagen hair syndrome, such as rectangular black granular structures, solitary yellow dots, and a predominance of follicular units with single hairs.
16 citations
,
October 2003 in “Journal of The American Academy of Dermatology” This study describes a 4-year-old boy who exhibits a rare, synchronized pattern of hair growth and shedding, unlike the typical asynchronous pattern seen in humans.
13 citations
,
July 2016 in “Pediatric Dermatology” This study found that loose anagen syndrome was more common in females and observed across all hair colors and skin types.
13 citations
,
March 2014 in “Pediatric Dermatology” This case report observed that a 2-year-old girl with loose anagen hair syndrome experienced rapid and significant improvement without adverse effects from tapered minoxidil 5% treatment over 28 months.
12 citations
,
March 2018 in “Australasian Journal of Dermatology” This letter to the editor discusses the use of systemic minoxidil for loose anagen hair syndrome, noting a significant change in hair color, but reports no new study results.
9 citations
,
December 2020 in “British Journal of Dermatology” This research letter reports that low-dose oral minoxidil improved hair density and length in children with loose anagen hair syndrome.
8 citations
,
August 2013 in “Pediatric Dermatology” This article reviews loose anagen hair syndrome, an inheritable hair disorder affecting children and sometimes adults, but does not report any new clinical results.
5 citations
,
January 2016 in “International Journal of Trichology” This case report describes two patients who experienced loose anagen hairs and pili torti, resulting in nonscarring alopecia, potentially linked to erlotinib treatment for solid tumors.
5 citations
,
November 2012 in “Journal of the American Academy of Dermatology” This case report describes a 3-year-old girl with short hair since birth, showing normal hair density with many vellus and intermediate hairs, and no hair shaft abnormalities.
3 citations
,
July 2016 in “International Journal of Dermatology” This case report describes an Asian girl with short anagen syndrome who experienced improved hair density after using minoxidil.
2 citations
,
March 2015 in “Hepatitis Monthly” This case report identified dystrophic anagen effluvium as a previously unreported dermatological side effect of PEG-INF-α-2a/RBV combination therapy in a patient with chronic hepatitis C infection.
1 citations
,
September 2023 in “British journal of dermatology/British journal of dermatology, Supplement” The researchers reported that WNT10A gene variants are linked to short anagen hair syndrome, which suggests a potential genetic factor contributing to this hair condition.
1 citations
,
December 2022 in “Skin Appendage Disorders” This study explores various tests that can be performed during teledermatology visits, such as self-conducted pull tests and ponytail thickness measurements, along with imaging tools, to assess hair loss virtually.
1 citations
,
January 2020 in “Skin appendage disorders” This case study documents the co-existence of trichorhinophalangeal syndrome and loose anagen syndrome in a patient, highlighting a previously unreported association between the two conditions.
1 citations
,
January 2014 in “Hair therapy & transplantation” This case study reports the first extensively interpreted instance of dystrophic telogen effluvium potentially linked to pegylated interferon and ribavirin therapy for chronic hepatitis C, characterized through clinical and trichogram analysis.
1 citations
,
January 2011 in “Journal of the American Academy of Dermatology” The combination of minoxidil and cyclosporine improved hair growth in short anagen syndrome.
Loose anagen hair syndrome in children may improve with age, but treatment results vary.
July 2025 in “Journal of Dermatological Treatment” This study found that platelet-rich plasma significantly improved hair growth parameters in androgenic alopecia patients and was even more effective when combined with minoxidil, particularly in reducing vellus hair.
This study explored a mother and daughter with loose anagen hair syndrome linked to wooly hair, identifying an intronic variant in the KRT71 gene that affects hair keratin splicing, thus broadening the spectrum of KRT71-related disorders.
February 2025 in “Journal of Dermatological Treatment” The study explores the potential effectiveness of low-dose oral minoxidil in treating short anagen hair syndrome, suggesting it may be a viable treatment option despite the condition often resolving spontaneously with puberty.
April 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” A new change in the WNT10A gene caused a condition leading to short hair growth in a Chinese family.
April 2024 in “Journal of the American Academy of Dermatology” Low-dose minoxidil helps hair grow longer and thicker in people with short anagen syndrome.
January 2024 in “Open MIND” This study identified five genes with rare variants potentially involved in male pattern hair loss and found no significant genetic or epidemiologic link between MPHL and severe COVID-19.
November 2023 in “British Journal of Dermatology” Mutations in the WNT10A gene cause Short Anagen Hair syndrome and increase the risk of male pattern hair loss.