2 citations
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June 2017 in “Psychiatry and clinical psychopharmacology” This case report describes the first known instance of hair loss linked to agomelatine, which resolved after the drug was discontinued.
June 2025 in “Frontiers in Neurology” This study found a significant association between finasteride use and increased risk of memory impairment, highlighting the need for risk communication and routine cognitive monitoring for long-term users.
7 citations
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March 2024 in “Journal of Neuroendocrinology” In this study, researchers found that both direct and witnessed trauma in mice are associated with reduced levels of the neurosteroid allopregnanolone, potentially influencing PTSD outcomes, and that treatment with synthetic neurosteroids may mitigate fear responses linked to observed trauma.
19 citations
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January 2012 in “Frontiers in Neural Circuits” This study found that neurosteroids and benzodiazepines decrease network excitability in neuronal cultures, with specific long-term depressive effects on inhibitory neurons.
January 2026 in “Hormones and Behavior” In this study, researchers observed that reproductive experience in female rats altered fear memory and medial prefrontal cortex (mPFC) activity, with pregnant and parous rats showing impaired fear recall compared to nulliparous controls, highlighting the influence of pregnancy-related neurosteroids on cognitive function and brain activity.
June 2013 in “Clinical Neurophysiology” Finasteride improved reflexes and motor activity in rats with liver-related brain issues.
11 citations
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December 2012 in “Alcoholism Clinical and Experimental Research” This study found that in Withdrawal Seizure-Prone mice, ethanol withdrawal decreased the sensitivity of GABA A receptors to GABAergic neurosteroids in certain areas of the brain.
3 citations
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September 2024 in “Brain and Behavior” This study found that combining ASA with conditioned medium from adipose tissue-derived MSCs may offer a promising approach for protecting against hippocampal injuries, suggesting potential synergistic therapeutic benefits that merit further investigation.
12 citations
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August 2018 in “Psychiatry research” This study found that estazolam improved PTSD-like behavior deficits in an animal model, which was linked to increased allopregnanolone levels in specific brain regions.
1 citations
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November 2023 in “Indian Journal of Science and Technology” In this study, researchers identified several active metabolites in Eclipta alba, demonstrated strong interaction with Alzheimer's disease proteins, and found that 28 days of treatment improved memory without significant toxicity in rats, suggesting potential pathways for treating Alzheimer's.
182 citations
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June 2002 in “Journal of Neuroscience” This study suggests that apoE4 may contribute to cognitive decline by reducing androgen receptor levels in the brain, but androgen treatment improved memory deficits in female mice expressing human apoE4.
1 citations
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March 2016 in “Neurotoxicity Research” In this study, finasteride pretreatment led to EEG changes in rats that suggest a mild reduction in thioacetamide-induced hepatic encephalopathy.
April 2008 in “Annals of General Psychiatry” This study found that social isolation in rats enhanced the effects of ethanol on certain brain steroids, increased GABAA receptor subunits, and amplified ethanol's inhibitory effects on seizures.
21 citations
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September 2008 in “Brain Research” Neurosteroids in the brain can increase or decrease seizure risk in mice.
This abstract is a navigation and policy notice for a website and does not contain any research findings.
4 citations
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December 2010 in “Journal of the American Geriatrics Society” This case report observed that delirium can be the sole symptom of a stroke, as seen in an elderly patient with a thalamic hemorrhage, highlighting the need to consider stroke in the differential diagnosis when delirium is present without focal neurological signs.
5 citations
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December 2019 in “JAAD Case Reports” This paper discusses anagen effluvium, a reversible non-scarring hair loss often triggered by certain chemotherapy drugs, but presents no new clinical results.
1 citations
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January 2015 in “Der pharmacia lettre” This study found that neurosteroids might play a role in the neuroprotective effects of ischemic postconditioning by reducing brain infarct size and improving motor performance and memory in mice.
December 2015 in “PLOS ONE” This content contains no study findings or new results, instead referring only to statistical methods and figure captions.
2 citations
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July 1988 in “JAMA” This article discusses reported cases of diffuse scalp hair thinning in women using amphetamines and suggests no clear cause-effect relationship with amphetamine use based on available evidence.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that both direct and witnessed trauma in mice were linked to lower levels of the neurosteroid allopregnanolone, and that boosting neurosteroidogenesis may alleviate PTSD-like symptoms, suggesting potential treatment strategies for PTSD stemming from either trauma type.
1 citations
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July 2015 in “The European research journal” This case report describes reversible hair loss in a patient taking aripiprazole, suggesting this side effect may be common among psychotropic medications.
May 2026 in “European Cells and Materials” In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.
2 citations
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January 2012 in “Australian and New Zealand journal of psychiatry” Haloperidol decanoate can cause alopecia areata.
June 2008 in “Alcoholism Clinical and Experimental Research” This study discusses how chronic ethanol exposure and withdrawal affect GABAA receptor subunit expression and function, finding that some changes can be selectively blocked by certain drugs like diazepam and finasteride.
January 2024 in “International journal of molecular sciences” This study found that boosting the synthesis of neural-derived 17β-estradiol effectively counteracted the impairment of hippocampal long-term potentiation caused by amyloid beta 1-42 in rat hippocampal slices, with the effect seemingly linked to glutamate NMDAR signaling.
1 citations
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October 2013 in “A & A case reports” In this case report, a patient experienced hair loss after a surgical procedure but did not encounter the same issue following a later surgery with similar anesthesia.
1 citations
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December 2024 in “The Journal of Dermatology” This study concluded that physical and emotional neglect could significantly contribute to the onset of alopecia areata, with alexithymia and traumatic stress disorder symptoms potentially more common in affected patients.
December 2024 in “Ukrains kyi Visnyk Psykhonevrolohii” This study found that women with mixed alopecia experienced significant cognitive impairments, particularly those with adaptation disorders, with symptoms like rapid fatigue and impaired concentration being most prevalent. The cognitive patterns are complex and require further investigation to inform tailored rehabilitation strategies.
4 citations
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January 2018 in “General Physiology and Biophysics” In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.