September 2024 in “Annals of Medicine and Surgery” In this review, the authors highlight the FDA approval of Ritlecitinib, the first oral treatment specifically for moderate to severe alopecia areata in patients aged 12 and older, marking a significant advancement in managing this condition.
March 2026 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” In this study, patients with resistant alopecia areata treated with 35% trichloroacetic acid showed significantly better outcomes compared to those receiving superficial cryotherapy, with TCA demonstrating "excellent" results in 37.5% of cases versus 6.25% for cryotherapy.
August 2018 in “Journal of The American Academy of Dermatology” Ozenoxacin 1% cream is an effective and safe treatment for impetigo in children and adults.
September 2022 in “Journal of the American Academy of Dermatology” This study observed that tofacitinib therapy over about 16 weeks had a positive effect in children with alopecia areata, reducing the SALT index significantly in some patients.
December 2006 in “The Brown University Psychopharmacology Update” This review discusses various psychiatric treatments including antipsychotics, insomnia medication, and mood stabilizers, but reports no new clinical results; the authors comment on existing findings and approvals.
9 citations
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May 2019 in “Vestnik dermatologii i venerologii” This study demonstrated a method for delivering a photosensitizer, Ammi majus fructuum furocumarines, into hair follicles using calcium carbonate particles, followed by UVA irradiation, which led to significant pigment accumulation, indicating potential improvements for photochemical therapy.
February 2024 in “PloS one” This review concluded that oral tofacitinib and adalimumab are promising treatments for cicatricial alopecia, showing effectiveness in improving signs and symptoms but requiring regular monitoring for adverse effects. The authors emphasize the need for further extensive studies to solidify these findings.
12 citations
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June 2017 in “Dermatologic therapy” This study reported that dithranol treatment up to 3% concentration led to hair regrowth in alopecia areata patients who had previously failed ultra-potent steroids, with regrowth observed across all severity levels.
October 2006 in “Clinical Cancer Research” This study found that doxorubicin-induced oxidative stress downregulates FLIPs and phosphorylates EF2, sensitizing prostate cancer cells to TRAIL; antioxidants may reduce doxorubicin's effectiveness, warranting further investigation.
June 2026 in “British Journal of Dermatology” This audit of ritlecitinib prescribing for severe alopecia areata found that regional practices largely followed national guidelines but highlighted the need for better psychological assessments and more consistent use of SALT scoring to inform treatment continuation decisions after 36 weeks.
February 2026 in “Cureus” This case report suggests that crisaborole may be an effective alternative treatment for alopecia areata in pediatric patients, showing significant hair regrowth after two weeks in a 10-year-old girl.
In a hair-growth mouse model, this study reported that the novel AR antagonist candidate 39, derived from structural optimization of 14-P1, achieved similar efficacy to pyrilutamide with faster response and maintained safety, demonstrating potent AR antagonism and favorable pharmacokinetics with lower systemic toxicity risk.
November 2025 in “SKIN The Journal of Cutaneous Medicine” In this study on adolescents with severe alopecia areata, baricitinib treatment showed effective scalp, eyebrow, and eyelash regrowth after 52 weeks, benefiting both responders and partial or non-responders, potentially reducing the psychosocial impact of the disease.
June 2024 in “Military Medicine” Access to JAK inhibitors for alopecia areata should be improved in the Military Healthcare System.
November 2023 in “Journal of Investigative Dermatology” JAK inhibitors are effective and generally safe for treating alopecia areata, but monitoring for side effects is important.
December 2025 in “Drug Design Development and Therapy” This retrospective study reported that in HER-2-negative metastatic breast cancer patients, anlotinib combined with taxane/capecitabine showed superior disease control rate, progression-free survival, and overall survival compared to bevacizumab plus chemotherapy, with both treatments having tolerable safety profiles.
January 2017 in “Brazilian Journal of Pharmaceutical Sciences” This study identified neprilysin as a potential target of the pharmacological agent arteannuin, which may guide future research into its clinical applications, although experimental verification is needed.
7 citations
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July 2019 in “International journal of research in dermatology” This study reported that intralesional triamcinolone acetonide was more effective than intralesional PRP for treating scalp alopecia areata, with minimal recurrence and side effects like atrophy and hypopigmentation.
This study found that a short-term treatment with all-trans retinoic acid may effectively stabilize platelet counts in idiopathic thrombocytopenic purpura patients experiencing fluctuations during thrombopoietin receptor agonist therapy.
13 citations
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December 2007 in “The Journal of Dermatology” This study reports two cases of alopecia areata that responded to the antihistamine fexofenadine.
This study found that the optimized topical AR antagonist 39, derived from 14-P1, demonstrated potent AR antagonism and comparable efficacy to pyrilutamide in a hair-growth mouse model, with a faster onset and favorable safety profile.
May 2023 in “Advancements in Homeopathic Research” This study investigated the effectiveness of a botanical formulation, Zauberӧl®, on testosterone-induced alopecia in Wistar rats, focusing on ingredients such as Arnica montana and Hibiscus Rosa sinensis. Results are not reported in the abstract.
This study found that baricitinib, a selective Janus kinase inhibitor, led to significantly improved scalp coverage in alopecia areata patients over 36 weeks compared to placebo, though adverse effects like acne and urinary tract infections were reported.
September 2023 in “Drugs in context” This article discusses baricitinib, a JAK1 and JAK2 inhibitor, as an approved and promising treatment for alopecia areata but reports no new clinical results.
1 citations
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May 2017 in “InTech eBooks” This review summarizes current treatments for recalcitrant alopecia areata and recent therapeutic developments targeting specific immunological pathways, reporting no new clinical results.
65 citations
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April 1999 in “Journal of Parasitology” This study found that all lesions in mice treated with a new topical formulation, WR 279,396, healed completely without relapse, outperforming other formulations and showing no toxicity.
January 2010 in “USFEU Scientific Library (Ural State Forest Engineering University)” This study developed a grooved microneedle platform enabling precise transdermal delivery of triamcinolone acetonide for alopecia areata, achieving accurate dosing by controlling groove position and drug concentration.
March 2022 in “Journal of Pakistan Association of Dermatologists” This case report describes a 64-year-old man with pulmonary nocardiosis, where erythema annulare centrifugum lesions possibly associated with co-trimoxazole resolved after discontinuation of the medication.
November 2025 in “JEADV Clinical Practice” In this retrospective cohort study, patients using leflunomide for primary autoimmune conditions showed a decreased risk of developing alopecia areata, while those using methotrexate, cyclosporine, and rituximab had an increased risk.
In a retrospective clinical study, this research found that baricitinib is effective for alopecia areata, with 42.3% of patients achieving a significant reduction in hair loss by week 36, and 52.4% by week 52, outperforming previous trials.