Effectiveness of Baricitinib in Alopecia Areata

March 2025

J Alvero-Roldán, P Barriga-Rodríguez, E Montecatine-Alonso, A López Gómez, M López-Feijoo, S Flores Moreno

baricitinib alopecia areata Severity of Alopecia Tool SALT score hypercholesterolemia

This study evaluated the effectiveness of baricitinib in treating alopecia areata (AA) in a cohort of 39 patients, with a focus on achieving a Severity of Alopecia Tool (SALT) score of ≤20. At 36 weeks, 42.3% of patients reached this target, and at 52 weeks, 52.4% did, indicating baricitinib's efficacy over time. These results surpass those from previous clinical trials (BRAVE-AA1 and BRAVE-AA2), where only 34% achieved a SALT ≤20 at 36 weeks. Despite the small sample size, the study supports baricitinib as an effective long-term treatment for AA, with hypercholesterolemia being the most common adverse event.

View this study on ejhp.bmj.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 15 results

community Pelage are going to do two phase 3 trials for PP405. How long will it take to complete two phase 3 trials?

in Chat 45 upvotes 1 month ago

Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.

community What are the odds baricitinib will get a topical otc version for androgenic alopecia?

in Research/Science 3 years ago

Baricitinib, approved for alopecia areata, might be considered for treating receding hairlines. The discussion is about the possibility of an over-the-counter topical version for androgenic alopecia.

community Lilly to seek first approval of an autoimmune drug for hair loss

in Research/Science 20 upvotes 4 years ago

Eli Lilly's drug baricitinib showed effectiveness in treating alopecia areata, with higher doses resulting in significant hair regrowth compared to placebo. The treatment is not for male pattern baldness.

community Anyone else taking Litfulo (ritlecitinib) to treat their alopecia?

in Treatment 7 upvotes 2 years ago

A user diagnosed with Alopecia Areata started using Litfulo (ritlecitinib), kenalog shots, and mometasone furoate 0.1%. They shaved their head and are seeking others' experiences with Litfulo.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Olumiant active ingredient Baricitinib

in Research/Science 1 upvotes 3 years ago

The conversation is about someone inquiring if anyone has tried Olumiant or its active ingredient, Baricitinib, for hair loss, mentioning the cost and that they have ordered Baricitinib.

Related Research

1 / 1 results

research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.