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Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.

Finasteride might affect memory by impacting cholinergic system.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Human skin can make serotonin and melatonin.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.