April 2012 in “Informa Healthcare eBooks” Alopecia areata is a common autoimmune condition causing varying hair loss, diagnosed by specific patterns of inflammation around hair follicles, with several treatment options available.
June 2006 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” Melatonin may help reduce the needed dose of prednisolone and improve hair growth in alopecia areata patients.
The patient with total hair loss did not regrow hair despite treatment, indicating a poor outlook for this type of hair loss.
January 1991 in “Journal of Pediatric Health Care” Hair loss in children can be caused by fungal infections, trauma, autoimmune disorders, or stress, and treatments vary depending on the cause.
April 1969 in “Postgraduate medicine” Use corticosteroid cream and triamcinolone injections for treating alopecia areata, and consider wigs and tranquilizers for support.
421 citations,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
222 citations,
September 2016 in “JCI insight” Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.
164 citations,
April 2008 in “Cochrane library” Current treatments for alopecia show no significant long-term benefits.
151 citations,
February 2007 in “International Journal of Dermatology” Alopecia areata causes hair loss, has no cure, and various treatments exist.
139 citations,
November 2016 in “Journal of the American Academy of Dermatology” Tofacitinib helped regrow hair in most adolescents with alopecia areata, but more research is needed.
131 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
128 citations,
February 2016 in “British Journal of Dermatology” Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.
122 citations,
April 1995 in “Journal of Cutaneous Pathology” The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
104 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.
101 citations,
November 1992 in “Archives of Dermatology” Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.
101 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil solution helps hair regrowth in alopecia areata, with 5% being more effective.
89 citations,
March 2018 in “The Journal of Dermatology” Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.
89 citations,
October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
76 citations,
July 2011 in “Clinical, Cosmetic and Investigational Dermatology” The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.
73 citations,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Some women with common hair loss may develop permanent hair loss.
72 citations,
July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
72 citations,
January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
63 citations,
May 2017 in “American Journal of Clinical Dermatology” People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.
62 citations,
October 2016 in “Dermatologic Therapy” PRP more effective than minoxidil 5% for treating alopecia areata.
59 citations,
January 2002 in “Dermatology” A new type of sudden, complete female hair loss was found, with most patients fully recovering within 6 months without needing steroid treatment.
55 citations,
October 2019 in “Dermatology and therapy” Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.
54 citations,
March 1987 in “Journal of The American Academy of Dermatology” 3% topical minoxidil effectively treats extensive alopecia areata with few side effects.
49 citations,
January 2003 in “Clinical and Experimental Dermatology” The document concludes that post-menopausal frontal fibrosing alopecia is a poorly understood condition that does not respond well to common treatments.
49 citations,
November 1992 in “Archives of dermatology” Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.