February 2025 in “Journal of the European Academy of Dermatology and Venereology” This study found that ultraviolet-induced fluorescence dermoscopy enhanced the identification of follicular openings in alopecia areata, potentially aiding in the assessment of disease severity and treatment strategies.
3 citations
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February 2020 in “The journal of gene medicine” This study found a recurrent nonsense mutation in the HR gene linked to atrichia with papular lesions in two Kashmiri families, suggesting whole exome sequencing as an efficient method for diagnosis and genetic counseling.
53 citations
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May 1996 in “The Journal of Clinical Endocrinology & Metabolism” This study identified multiple mutations in the 5 alpha-reductase-2 gene among male pseudohermaphrodites in the Dominican Republic, suggesting they do not share a common ancestry.
114 citations
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August 2002 in “Journal of Investigative Dermatology” Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
January 2022 in “Al-Azhar Medical Journal” This study found a significant association between antigliadin antibodies (IgA and IgG) and alopecia areata severity, suggesting a need for celiac disease screening in these patients.
3 citations
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June 2023 in “Journal of cosmetic dermatology” This study reported improvement in an 11-year-old boy with refractory alopecia areata after 4 months of treatment with oral abrocitinib, a JAK1 inhibitor, suggesting it may be a potential alternative for pediatric patients unresponsive to conventional therapies.
6 citations
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July 1976 in “JAMA” This article discusses dermatological issues associated with black skin, such as postinflammatory pigmentation and keloids, and highlights the need for practitioners to understand these racial characteristics; it reports no new clinical results.
21 citations
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October 2007 in “Australasian Journal of Dermatology” This case study reported that a 62-year-old woman with alopecia areata experienced significant hair regrowth with completely non-pigmented white hair following a 2-month course of oral prednisolone.
May 2014 in “JAMA Dermatology” Mother and son diagnosed with a rare genetic hair loss condition with no effective treatment.
July 2024 in “Journal of Pakistan Association of Dermatologists” In this study of alopecia areata patients, researchers reported that nail changes are significantly associated with severe disease, and dermoscopic analysis revealed a notable correlation between yellow dots and increased disease severity, with the condition primarily affecting young adults and more common in males.
9 citations
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February 2002 in “PubMed” This study identified a novel mutation in the coproporphyrinogen oxidase gene, contributing to hereditary coproporphyria in a family, with decreased enzyme activity observed in the affected members.
July 2010 in “Journal of Investigative Dermatology” Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
2 citations
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August 1994 in “Archives of dermatology” This article reports a case of a 19-month-old boy with scalp erythematous papules and hair loss, showing no improvement with initial treatment.
3 citations
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August 2017 in “Clinical case reports” A rare skin condition causes red and dark patches on the face and limbs.
54 citations
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October 2007 in “The FASEB Journal” This study suggests that hairlessness in nude mice may be due to insufficient expression of phospholipase C-δ1, a molecule essential for normal hair development downstream of the Foxn1 gene.
September 2017 in “Journal of Investigative Dermatology” This study found that in AGA, the risk allele at locus 2q35 alters WNT10A expression through EBF1, suggesting a potential androgen-dependent regulatory mechanism.
11 citations
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December 2015 in “Indian journal of dermatology, venereology, and leprology” Dermoscopy quickly and accurately diagnosed a rare hair disorder in a 12-year-old girl.
December 2025 in “Frontiers in Medicine” This review details the global mutation patterns of genes associated with autosomal recessive woolly hair/hypotrichosis and highlights potential, yet unproven, treatments like minoxidil and regenerative therapies, reporting no new clinical results.
44 citations
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August 2004 in “Journal of Investigative Dermatology” A gene deletion in DSG4 causes sparse hair in some Pakistani families.
August 2023 in “Journal of Dermatological Science” A specific RNA molecule blocks hair growth by affecting a protein related to hair loss conditions.
August 2022 in “Brain and Development” In this case report, a nine-year-old girl with both chronic inflammatory demyelinating polyneuropathy and alopecia universalis showed improvement in muscle weakness and hair loss after treatment with intravenous immunoglobulin and corticosteroids.
16 citations
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July 2021 in “American Journal of Medical Genetics Part A” This study identified novel LSS mutations implicated in hypotrichosis simplex with or without neurodevelopmental abnormalities, highlighting the need for careful evaluation of synonymous mutations' potential pathogenic effects.
March 2019 in “Our Dermatology Online” A woman with severe hair loss regrew mostly white hair after treatment.
2 citations
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April 2025 in “Pediatric Dermatology” This study identified and described a new form of alopecia termed "macular alopecia," predominantly affecting young Hispanic/Latinx females, characterized by small macules on the scalp with a high rate (63%) of spontaneous resolution in about five months.
23 citations
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April 1993 in “Gastroenterology” This study reported a case where cyclosporine treatment in a child led to remission of ulcerative colitis and regrowth of scalp and body hair, suggesting a possible connection between the disorders.
September 2022 in “JAAD case reports” This case study of a 45-year-old man from Tonga describes the identification of pachyonychia congenita through genetic testing, revealing a mutation in the keratin gene KRT16, associated with chronic painful skin and nail conditions.
May 1979 in “Archives of Dermatology” This review discusses the associations between nonscarring alopecia and conditions like vitiligo and autoimmune reactions, but reports no new clinical results.
July 2024 in “Journal of Investigative Dermatology” Alopecia areata patients are more likely to develop keloids, especially if they also have atopic dermatitis.
August 2023 in “Sabuncuoglu Serefeddin Health Sciences” This study investigated genetic markers for alopecia areata in the Turkish population, finding that the CT60 polymorphism might be linked to increased susceptibility, while no such association was found for the +49AG polymorphism; further studies are needed to confirm these findings.
13 citations
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January 2011 in “International Journal of Trichology” CTA is often mistaken for AA but doesn't respond to steroids and may require hair transplantation.