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research Harnessing Physiology to Understand Mechanisms Underpinning Frailty
Understanding how different body systems interact can improve how we prevent or treat frailty in aging.
research Flavonoid 4,4'-Dimethoxychalcone Selectively Eliminates Senescent Cells Via Activating Ferritinophagy
The substance DMC helps get rid of aging cells by triggering a process that causes cell death, which could treat age-related diseases.
research Embryonic-Like Regenerative Phenomenon: Wound-Induced Hair Follicle Neogenesis
New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
research Advanced Glycation End-Products Inhibit Mesenchymal-Epidermal Interaction by Up-Regulating Proinflammatory Cytokines in Hair Follicles
AGEs may cause hair loss by increasing inflammation in hair follicles.
research Clinical Biochemistry of Dihydrotestosterone
Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
research Current Issues of Skin Aging and Strategies for Its Correction
Skin aging can be slowed down with proper care and treatments.
research Reproductive Seasonality and Maturation Throughout the Complete Life-Cycle in the Mouflon Ram (Ovis Musimon)
Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.
research Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp
Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.
research T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus
Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
research Cognitive, Emotional, Physical, and Behavioral Stress-Related Symptoms and Coping Strategies Among University Students During the Third Wave of COVID-19 Pandemic
University students in Egypt experienced high stress during COVID-19's third wave, with negative coping mechanisms being more common.
research Fractal Pattern in the Premature Graying of Hair: A Case Report
A 32-year-old man with early graying hair shows a unique pattern, suggesting more research is needed on why hair grays early.
research Premature Graying of Hair: Ayurveda Perspective
Ayurveda can help treat premature hair graying with lifestyle changes and herbal remedies.
research Clinical and Epidemiological Characteristics and Associated Factors of Hair Graying: A Population-Based, Cross-Sectional Study in Turkey
Most people in Turkey start getting gray hair around 33 years old, with factors like age, education, hair loss, skin type, family history, and anxiety playing a role.
research Identifying Molecular Targets for Reverse Aging Using Integrated Network Analysis of Transcriptomic and Epigenomic Changes During Aging
Curcumin may help reverse aging by targeting specific genes.
research Genetic Predictors of Testosterone and Their Associations with Cardiovascular Disease and Risk Factors: A Mendelian Randomization Investigation
Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.
research Trichoscopic Findings in Children and Adults with Alopecia Areata: A Comparative Study
Children with alopecia areata have more exclamation mark hairs and fewer yellow dots than adults.
research Compendium of Polycystic Ovarian Syndrome and Its Relevance in Glycation and Diabetes
PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
research Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
Baricitinib reduces inflammation and improves cell health in premature aging cells.
research Aging and Colony-Forming Efficiency of Human Hair Follicle Keratinocytes
Aging reduces the ability of human hair follicle cells to form new cell colonies.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Trichoscopy of Alopecia Areata in Children: A Retrospective Comparative Analysis of 50 Children and 50 Adults
Children with alopecia areata have different trichoscopic features than adults, including more empty follicular openings and pigtail hairs.
research Alopecia and Its Association with Coronary Heart Disease and Cardiovascular Risk Factors: A Meta-Analysis
People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
research Follicular Delivery of Caffeine from a Shampoo for Hair Retention
The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.
research Efficacy and Safety of Docetaxel in the Elderly
Docetaxel is safe and works well for older people with cancer, with manageable side effects.
research Wound-Induced Hair Neogenesis: A Novel Paradigm for Studying Regeneration and Aging
Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
research How the Stress of Fight or Flight Turns Hair White
Stress turns hair white by depleting color-giving cells in hair follicles through a specific neurotransmitter related to the body's stress response.
research Hair Through the Female Life Cycle
Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.
research Cell Therapy for Androgenetic Alopecia: Elixir or Trick?
Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.
research Study of Frontal Hairline Patterns in Spanish Caucasian Women
Most Spanish Caucasian women have a widow's peak, and their hormone levels suggest they process certain hormones faster.