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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Birth control pills and cyproterone acetate can help treat acne in women, especially when linked to hormonal issues.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

Adalimumab helped control a child's severe eye disease when other treatments failed.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Inhaled steroids in children may cause excessive hair growth and not always go away after stopping the medication.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

Skin health and diseases are closely linked to metabolic processes.

The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.

Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

PCOS is diagnosed when at least two of these three features are present: polycystic ovaries, irregular ovulation, and high androgen levels.

GnRH analogues are effective for diagnosing and treating female androgen excess, offering a non-surgical option.

Cimetidine cream shows potential for treating warts and female-pattern hair loss.

Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Excess androgens may cause PCOS, not just be a symptom.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.