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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.

Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.

TGF-β2 plays a key role in human hair growth and development.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Fat cells are important for tissue repair and stem cell support in various body parts.

Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

New drug delivery methods can make natural compounds more effective and stable.

GLI2 increases follistatin production in human skin cells.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.

Capecitabine is as effective as intravenous treatments with fewer side effects, but requires careful management of Hand-foot syndrome and patient education.

Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.

ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Minoxidil and caffeine in transfersomes improve hair growth treatment.