2 citations
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August 2020 in “Journal of Nutritional Science and Vitaminology” In this study, yellow Chinese chive extract was observed to protect against acetaminophen-induced liver toxicity in mice by enhancing antioxidant pathways and reducing liver injury markers.
January 2026 in “E3S Web of Conferences” This study found that silver nanoparticles synthesized using Mitracarpus scaber extract showed potential hepatoprotective and anti-hyperplastic effects in rats, suggesting novel therapeutic strategies for managing liver injury and benign prostatic hyperplasia.
November 2024 in “Asian Journal of Biological Sciences” In this animal study, researchers reported that acetaminophen increased LH and FSH hormones in male rats, with high doses affecting sperm production negatively, while avocado leaf extract reduced sperm motility and viability, suggesting potential adverse effects on male reproductive health.
May 2024 in “International journal of medicine and psychology.” This study found that ibuprofen was more effective than acetaminophen in reducing postoperative pain and inflammation after lower molar extraction, with patients experiencing lower pain scores and better reductions in inflammatory markers CRP and IL-6.
2 citations
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May 2009 in “Hair transplant forum international” This abstract discusses facial swelling as a temporary complication of hair transplantation and indicates that multiple prevention methods have been tested, but it reports no new results.
2 citations
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January 2018 in “Biomolecules & therapeutics” This study found that polyamidoamine dendrimers can permeate skin's current conducting pores and alter the magnitude and direction of electroosmotic flow, affecting drug flux during iontophoresis.
January 2026 in “Springer Link (Chiba Institute of Technology)” In this study, researchers synthesized silver nanoparticles using an extract from Mitracarpus scaber and found them to have significant hepatoprotective and anti-hyperplastic effects in rats, suggesting potential for treating liver injury and benign prostatic hyperplasia.
8 citations
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May 2024 in “ACS Applied Materials & Interfaces” This study found that incorporating PCL-based nanoscaffolds into liver spheroids enhances their viability and liver-specific biofunctionality, suggesting these scaffolds improve the model's potential for preclinical drug screening by increasing sensitivity to acetaminophen toxicity compared to traditional methods.
64 citations
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January 2001 in “Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy” This review discusses the diverse pharmacological activities of misoprostol across multiple health conditions but reports no new clinical data, highlighting potential applications beyond its traditional uses.
September 2023 in “Translational medicine reports” This case study reported that an 18-year-old woman ingested a large amount of topical minoxidil, leading to symptoms like low blood pressure, increased heart rate, and elevated liver enzymes, but recovered fully after treatment. Minoxidil toxicity may rarely cause abnormal liver enzyme levels.
The man has patchy hair loss likely due to alopecia areata.
This handbook of dermatology provides a comprehensive practical manual for dermatologists, but reports no new research findings.
1 citations
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October 2000 in “Pediatrics in Review” The document says that hookworms are treated with mebendazole and stress-related hair loss usually gets better in 6 months, while other hair loss types have specific treatments.
The interdisciplinary approach improved the quality of life for a Parkinson's patient and eased staff workload.
284 citations
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November 1999 in “Neurology” This article discusses the side effects of interferon beta therapy for MS, including flu-like symptoms and autoimmune reactions, and provides guidance on their management but does not report new clinical findings.
26 citations
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March 2014 in “Rheumatology” This study confirms an association between TNF-α antagonist exposure and alopecia, indicating a class effect among the medications examined.
5 citations
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March 2016 in “Acute medicine & surgery” This case report describes a man who ingested a large amount of topical minoxidil solution and experienced serious and prolonged cardiovascular effects despite rapidly decreasing serum concentration levels.
1 citations
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September 2023 This study reported that the combination of tridax procumbens and ginger juice improved antioxidant activity and protected against liver damage induced by paracetamol in rats, suggesting a potent hepatoprotective effect.
January 2011 in “Annals of dermatology/Annals of Dermatology” During treatment with interferon/ribavirin for hepatitis C, this study observed significant and lasting improvement in a patient's psoriasis without additional psoriasis-specific therapies.
66 citations
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September 1982 in “Biochemical Pharmacology” This study identified a sulfotransferase activity in rat liver that catalyzes the sulfation of minoxidil, contributing to its delayed hypotensive effects.
275 citations
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March 1999 in “Journal of The American Academy of Dermatology” This review elaborates on the skin side effects of chemotherapy and emphasizes identifying and managing both common and life-threatening skin reactions, without presenting new clinical findings.
273 citations
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May 2017 in “The Lancet” This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.
237 citations
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February 2016 in “Science Translational Medicine” This study found that many effects previously thought to be caused by circadian rhythm disruption in Bmal1 knockout mice are actually due to BMAL1's properties unrelated to its clock function.
202 citations
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June 2005 in “Aaps Pharmscitech” This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
183 citations
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January 2018 in “Cosmetics” This review discusses side effects and allergy contact dermatitis caused by essential oils in cosmetic products and reports no new clinical results.
176 citations
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June 2016 in “PLoS ONE” In these initial clinical studies, NAP monotherapy showed significant reductions in HBsAg levels among patients with chronic HBV, suggesting potential as part of future combination therapies.
165 citations
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September 2003 in “Toxicology and applied pharmacology” This review discusses the pharmacology and toxicology of cyclooxygenase in skin, highlighting its role in inflammation, wound healing, and tumorigenesis, without presenting new clinical results.
155 citations
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June 2009 in “International Journal of Dermatology” This extensive review discusses the clinical manifestations, potential associations, and treatment approaches for lichen planus, but reports no new clinical results, highlighting gaps in evidence for therapeutic strategies.
123 citations
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September 1987 in “JAMA” This study observed that patients receiving IL-2 immunotherapy developed a skin eruption characterized by burning and pruritus, which resolved shortly after stopping the infusion, suggesting that IL-2 mediated these effects.
114 citations
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January 2007 in “Drug Safety” This review discusses various adverse drug reactions affecting the skin, hair, and nails, emphasizing the importance of recognizing and reporting these reactions but reports no new clinical findings.