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    Glossary Acanthosis Nigricans

    skin condition with dark, thick, velvety patches

    Acanthosis Nigricans (AN) is a skin condition characterized by dark, thick, and velvety patches, typically found in body folds and creases such as the neck, armpits, and groin. It is often associated with insulin resistance, obesity, and hormonal disorders, and can sometimes be a sign of an underlying health issue like type 2 diabetes or, in rare cases, cancer.

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    1. Mania in Hyperandrogenism, Insulin Resistance, and Nigricans Acanthosis Syndrome ˜The œAmerican journal of psychiatry · 2002 · 3 citations
    2. Hyperandrogenism insulin resistance-acanthosis nigricans syndrome in a female adolescent with migraine: A case report Indian Journal of Physiology and Pharmacology · 2025
    3. Acanthosis Nigricans during an HAIR-AN syndrome: "The Tree That Hides the Forest" Journal of clinical & experimental dermatology research · 2017
    4. Hyperandrogenism-insulin resistance-acanthosis nigricans syndrome with PCOS and Hashimoto's thyroiditis: case report International Journal of Research in Medical Sciences · 2015
    5. Acanthosis nigricans and the metabolic syndrome Clinics in Dermatology · 2017 · 30 citations
    6. Acanthosis nigricans in adolescents with polycystic ovary syndrome International journal of reproduction, contraception, obstetrics and gynecology · 2022
    7. Hyperandrogenism-Insulin Resistance-Acanthosis Nigricans Syndrome Case reports in endocrinology · 2015 · 7 citations
    8. The hyperandrogenic-insulin-resistant acanthosis nigricans syndrome: therapeutic response Fertility and sterility · 1994 · 23 citations
    9. Review of facial acanthosis nigricans: Easy to diagnose and difficult to treat marker of hyperinsulinemia/metabolic syndrome Medical Journal Armed Forces India · 2024 · 2 citations
    10. Insulin Resistance, Acanthosis Nigricans, and Polycystic Ovaries Associated with a Circulating Inhibitor of Postbinding Insulin Action The Journal of Clinical Endocrinology & Metabolism · 1985 · 24 citations
    11. ACANTHOSIS NIGRICANS IN OBESE VERSUS NON-OBESE IN A TERTIARY CARE HOSPITAL ASSOCIATION WITH BMI AND CENTRAL OBESITY Zenodo (CERN European Organization for Nuclear Research) · 2021
    12. Global hotspots and trends in Acanthosis nigricans research: A bibliometric and visualized analysis Skin Research and Technology · 2024 · 3 citations
    13. Rabson-Mendenhall syndrome: two case reports and a brief review of the literature Odontology · 2010 · 18 citations
    14. Skin disease related to metabolic syndrome in women International journal of women’s dermatology · 2019 · 11 citations
    15. An adolescent girl with coexisting ovarian mature cystic teratoma and HAIR-AN syndrome, an extreme subtype of polycystic ovarian syndrome Endocrinology, diabetes & metabolism case reports · 2021 · 2 citations
    16. Combination of metformin with liraglutide in treating HAIR-AN syndrome in children: A case report and literature review. PubMed · 2023
    17. A Rare Case of Adolescent Girl with Beard-PCOS with a Difference: “HAIR-AN Syndrome” 2022
    18. Syndromes of Severe Insulin Resistance (SSIRs) 2004
    19. Gynecologic and andrologic dermatology and the metabolic syndrome Clinics in Dermatology · 2017 · 14 citations
    20. A Complex Clinical Situation in Polycystic Ovary Syndrome: HAIR‐AN Syndrome ‘‘Case Report’’ Case Reports in Medicine · 2025
    21. Phenotype and metabolic profile of South Asian women with polycystic ovary syndrome (PCOS): results of a large database from a specialist Endocrine Clinic Human Reproduction · 2010 · 111 citations
    22. Diagnosis and management of the dermatologic manifestations of the polycystic ovary syndrome Dermatologic therapy · 2006 · 97 citations
    23. Polycystic ovary syndrome: A review for dermatologists Journal of the American Academy of Dermatology · 2014 · 60 citations
    24. Cutaneous Findings and Systemic Associations in Women With Polycystic Ovary Syndrome JAMA Dermatology · 2015 · 53 citations
    25. Polycystic Ovary Syndrome: A Common But Often Unrecognized Condition Journal of Midwifery & Women's Health · 2012 · 48 citations
    26. What every physician should know about polycystic ovary syndrome Dermatologic therapy · 2008 · 33 citations
    27. Clinical characteristics of polycystic ovary syndrome: investigating differences in White and South Asian women Clinical Endocrinology · 2015 · 29 citations
    28. Full investigation of patients with polycystic ovary syndrome (PCOS) presenting to four different clinical specialties reveals significant differences and undiagnosed morbidity Human Fertility · 2011 · 29 citations
    29. Síndrome do ovário policístico: abordagem dermatológica Anais Brasileiros De Dermatologia · 2011 · 26 citations
    30. Elevated fasting insulin is associated with cardiovascular and metabolic risk in women with polycystic ovary syndrome Diabetes and Metabolic Syndrome: Clinical Research and Reviews · 2019 · 17 citations