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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

New genes and pathways are important for testosterone production and male sexual development.

Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.

Vitamin D3 affects cell differentiation in specific skin areas.

Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Toxic Shock Syndrome cases increased due to new factors, but decreased with public health measures and changes in tampon use.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Cationic polymers improved liposome stability and increased skin absorption of aciclovir and minoxidil.