research Chronic Nonhealing Ulcer in a Finger of a Toddler – A Rare Presentation of Hair Thread Tourniquet Syndrome
A toddler's chronic finger ulcer was successfully treated after removing a hair causing hair-thread tourniquet syndrome.
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research Xanthomatous Hypophysitis: Always Think Twice Before Pituitary Resection
Always consider xanthomatous hypophysitis before deciding on pituitary surgery.
research 5α-Reduced Glucocorticoids: A Story of Natural Selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research A Novel and Safe Small Molecule Enhances Hair Follicle Regeneration by Facilitating Metabolic Reprogramming
Small molecule IM boosts hair growth by changing stem cell metabolism.
research The Effect of Platelet-Rich Plasma on Female Androgenetic Alopecia: A Randomized Controlled Trial
PRP injections improve hair density and thickness in women with hair loss.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
research 3,3-Diphenylpentane Skeleton as a Steroid Skeleton Substitute: Novel Inhibitors of Human 5α-Reductase 1
A new compound effectively inhibits human 5α-reductase 1.
research A Pure, Monolayer Culture of Merkel Cells from Sinus Hair Follicles of the Rat
Adding fetal calf serum helps Merkel cells survive and change shape.
research A Philosophy and Strategy for Surgical Hair Restoration: A 10-Year Experience
The authors' 10-year experience shows that a personalized approach to hair restoration surgery, using various techniques, leads to natural results and high patient satisfaction.
research A New Suture for Hair Transplantation
Poliglecaprone 25 is better than steel staples for hair transplant surgery, causing less discomfort and finer scars.
research A Segmental Approach to Scoring Hair Density from Global Images: Introducing the Scalp Coverage Scoring Method for Clinical Trials and Practice
The Scalp Coverage Scoring method reliably measures hair density from images.
research A Mouse Model for Studying Stem Cell Effects on Regeneration of Hair Follicle Outer Root Sheaths
The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
research A Philosophy and Strategy for Surgical Hair Restoration
Scalp reduction gives the most natural result for significant crown baldness, despite potential complications, and a systematic approach to surgical hair restoration results in few complications and high graft survival.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor
Finasteride effectively blocks enzyme causing male pattern baldness.
research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
research Benign Prostatic Hyperplasia: A Disorder of Androgen Metabolism in Males
Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.
research Discovery of a Novel Hybrid from Finasteride and Epristeride as 5α-Reductase Inhibitor
New hybrid compound found to effectively prevent hair loss.
research An Intrafamilial Transmission of Arthroderma Benhamiae in Canadian Porcupines (Erethizon Dorsatum) in a Japanese Zoo
Canadian porcupines in a Japanese zoo passed a skin fungus to each other.
research Scalp Extension: A Quantitative Study
Scalp extenders improve the results of scalp reduction for baldness but can cause severe headaches.
research Platelet-Rich Plasma for the Treatment of Female Pattern Hair Loss: A Patient Survey
PRP treatment satisfies 58% of female hair loss patients, with most noticing fuller, thicker hair and less shedding.
research Extractives of Cercidiphyllum Japonicum Twigs: Isolation and Structural Elucidation of a New Galloylflavonol Glycoside, Anomeric Tannins and Flavonoids
Scientists found a new natural compound and other known compounds in Cercidiphyllum japonicum twigs, which might be useful for medicine.
research Newly Born Mesenchymal Cells Disperse Through Rapid Mechanosensitive Migration
Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research AGD1, A Class 1 ARF-GAP, Acts in Common Signaling Pathways with Phosphoinositide Metabolism and the Actin Cytoskeleton in Controlling Arabidopsis Root Hair Polarity
AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target
Targeting CD200 could be a new treatment for rheumatoid arthritis.
research Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia
Finasteride effectively treats male hair loss, improving growth and density.
research 5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
research Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.