research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism
Finasteride is a safe, effective treatment for hirsutism with fewer side effects.
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research Saturable Binding of Finasteride to Steroid 5α-Reductase as Determinant of Nonlinear Pharmacokinetics
Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
research Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
research Assessment of the Usefulness of Dihydrotestosterone in the Diagnostics of Patients with Androgenetic Alopecia
DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
research Minoxidil: A Comprehensive Review
Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.
research Phytochemicals as Emerging Therapeutic Agents for Alopecia Treatment
Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.
research Androgenetic Alopecia in Women
Hair loss in women, often not related to male hormones, increases with age and can cause significant emotional distress.
research Bioprospecting of Potential Inhibitors of 5alpha Reductase 2 from Relevant Ethno-Pharmacological Plants via In Silico Techniques
Three natural compounds from Ghanaian plants may help treat BPH and alopecia.
research Separation of Finasteride and Analogues
Finasteride and analogues separated using LC-MS-MS technique.
research The 5α-Reductase Inhibitor Finasteride Is Not Associated With Alterations in Sleep Spindles in Men Referred for Polysomnography
Finasteride doesn't affect sleep spindles in men.
research Pharmacophore and Atom-Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
research Activity of Steroid 4 and Derivatives 4a–4f as Inhibitors of the Enzyme 5α-Reductase Type 1
Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
research Evaluation of Five Hundred Patients Using Ahmad’s NPRT System for Documenting Male Pattern Baldness
Ahmad's NPRT system accurately documents and predicts male pattern baldness.